The present paper intends to discuss the antioxidant and tyrosinase inhibition effect of solanesol from three aspects of ultraviolet radiation and free radical scavenging. The paper makes a survey on diurnal variation rule of the minimum ultraviolet transmittance and ultraviolet transmittance of solanesol, hydroxyl (·OH) free radical scavenging method of Smirnoff reaction system model, superoxide anion O2-· free radical scavenging method of pyrogallol autoxidation, and the inhibitory effect of solanesol on tyrosinase activity by enzyme kinetic method. The experiment results showed that solanesol could effectively scavenge lipid radicals to block lipid peroxidation, and inhibit effects on tyrosinase. Solanesol is a natural extract which could be used to prevent senile atrophy of human skin and senile plaque.
Citation：
BAIQi, YUJia, SUMei, BAIRui, KATUMATAGoroh, KATUMATAMasahiro, CHENXiushen. Antioxidant Function of Solanesol and Its Inhibitory Effect on Tyrosinase. Journal of Biomedical Engineering, 2014, 31(4): 833-836,841. doi: 10.7507/1001-5515.20140156
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Copyright © the editorial department of Journal of Biomedical Engineering of West China Medical Publisher. All rights reserved
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周敏,李利,周光平.黄芩甙对紫外线诱导人正常黑素细胞黑素合成的抑制作用研究[J].临床皮肤科杂志,2002,31(10):613-614.
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- 1. 马玉兰,侯天德,张继,等.茄尼醇的抗氧化实验研究[J].食品研究与开发,2011,32(2):8-12.
- 2. COCKELL C S. Biological effects of high ultraviolet radiation on early earth--a theoretical evaluation[J]. J Theor Biol, 1998, 193(4): 717-729.
- 3. SACHSENMAIER C, RADLER-POHL A, ZINCK R, et al. Involvement of growth factor receptors in the mammalian UVC response[J]. Cell, 1994, 78(6): 963-972.
- 4. BAADSGAARD O, WULF H C, WANTZIN G L, et al. UVB and UVC, but not UVA, potently induce the appearance of T6-DR+ antigen-presenting cells in human epidermis[J]. J Invest Dermatol, 1987, 89(1): 113-118.
- 5. CAMPBELL C, QUINN A G, ANGUS B, et al. Wavelength specific patterns of p53 induction in human skin following exposure to UV radiation[J]. Cancer Res, 1993, 53(12): 2697-2699.
- 6. 王廷豪,白琦,余凯,等.高纯度烟叶提取物茄尼醇含量测定及铅污染和抗氧化性能的初探[J].江苏农业科学,2011,4:347-348.
- 7. 郭晓强,颜军,邬晓勇,等.决明子水溶性多糖的纯化及抗氧化活性研究[J].食品科学,2007,28(8):205-208.
- 8. 叶孝兆,龚盛昭,廖国俊,等.当归提取物对酪氨酸酶的抑制作用[J].日用化学工业,2010,40(2):98-100,123.
- 9. 陈清西,宋康康.酪氨酸酶的研究进展[J].厦门大学学报:自然科学版,2006,45(5):731-737.
- 10. 周敏,李利,周光平.黄芩甙对紫外线诱导人正常黑素细胞黑素合成的抑制作用研究[J].临床皮肤科杂志,2002,31(10):613-614.
