• School of Electrical and Information Engineering, Jiangsu University of Technology, Changzhou, Jiangsu 213001, P. R. China;
WU Quanyu, Email: wuquanyu@jsut.edu.cn
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To address the current issues of data imbalance and scarcity in photoplethysmography (PPG) data for type 2 diabetes mellitus (T2DM) prediction, this study proposes an improved conditional Wasserstein generative adversarial network with gradient penalty (CWGAN-GP). The algorithm integrated gated recurrent unit (GRU) networks and self-attention mechanisms to construct a generator, aiming to produce high-quality PPG signals. Various data augmentation methods, including the improved CWGAN-GP, were employed to expand the PPG dataset, and multiple classifiers were applied for T2DM prediction analysis. Experimental results showed that the model trained on data generated by the improved CWGAN-GP achieved the optimal prediction performance. The highest accuracy reached 0.895 0, and compared with other data enhancement methods, this approach exhibited significant advantages in terms of precision and F1-score. The generated data notably enhances the accuracy and generalization ability of T2DM prediction models, providing a more reliable technical basis for non-invasive early T2DM screening based on PPG signals.

Citation: HU Mingying, WU Quanyu, CAO Yifan, CAO Jin, ZHAO Yifan, ZHANG Lin, LIU Xiaojie. Research on type 2 diabetes prediction algorithm based on photoplethysmography. Journal of Biomedical Engineering, 2025, 42(5): 1005-1011. doi: 10.7507/1001-5515.202501006 Copy

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