目的 总结手术联合放射性125I粒子植入治疗颈部及躯干部滑膜肉瘤的疗效。
方法 2010年5月－2012年5月，收治颈部及躯干部滑膜肉瘤患者4例。男3例，女1例；年龄33～68岁，平均50岁。病变位于颈后部、左颈根部、右腰背部和左肩胛下各1例。病变范围8 cm×6 cm×4 cm～12 cm×10 cm×6 cm。术中避开病变周围重要结构，尽量距病变周围2 cm以上彻底切除，病变切除区植入125I粒子并以皮瓣或肌皮瓣修复，供区植皮修复。
结果 术后患者皮瓣及植皮均成活，创面均Ⅰ期愈合。4例患者均获随访，随访时间18～36个月，平均26个月。皮瓣存活良好，局部均无肿瘤复发。其中1例于术后18个月因肺转移死亡。
结论 手术联合放射性125I粒子植入治疗颈部及躯干部滑膜肉瘤安全易行，可有效控制肿瘤局部复发。
Citation：
陈程, 岑瑛, 卿勇. 手术联合放射性125I粒子植入治疗颈部及躯干部滑膜肉瘤. Chinese Journal of Reparative and Reconstructive Surgery, 2015, 29(3): 393-394. doi: 10.7507/1002-1892.20150084
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- 1. Spillane AJ, A'Hern R, Judson IR, et al. Synovial sarcoma:a clinicopathologic, staging, and prognostic assessment. J Clin Oncol, 2000, 18(22):3794-3803.
- 2. Jang JW, Lee JK, Seo BR, et al. Synovial sarcoma of the posterior neck:a case report and review of literature. J Korean Neurosurg Soc, 2010, 47(4):306-309.
- 3. Jayaraman S, Rao SD, Govindarajan M. Synovial sarcoma of anterior abdominal wall. Indian J Surg, 2010, 72(Suppl 1):293-295.
- 4. Foreman SM, Stahl MJ. Biphasic synovial sarcoma in the cervical spine. Case report. Chiropr Man Therap, 2011, 19(1):12.
- 5. Singer S, Corson JM, Demetri GD, et al. Prognostic factors predictive for survivial of truncal and retroperitoneal soft tissue sarcoma. Ann Surg, 1995, 221(2):185-195.
- 6. Harb WJ, Luna MA, Patel SR, et al. Survival in patients with synovial sarcoma of the head and neck:association with tumor location, size, and extension. Head Neck, 2007, 29(8):731-740.
- 7. Huang Q, Chen J, Chen Q, et al. Computed tomographic-guided iodine-125 interstitial implants for malignant thoracic tumors. Eur J Radiol, 2013, 82(11):2061-2066.
- 8. Geiger EJ, Basques BA, Chang CC, et al. Wound healing complications with intraoperative brachytherapy for head and neck cancer:a unique form of radiation injury. Ann Plast Surg, 2014, 73(4):378-384.
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