目的 总结 1 例股骨中段骨促结缔组织增生性纤维瘤（desmoplastic fibroma of bone，DF）并病理性骨折诊治经验。方法 2015 年 6 月，1 例 40 岁男性患者因摔倒致右大腿疼痛并功能障碍 6 h 入院。入院后经体检、X 线片以及 CT 检查诊断为股骨中段骨囊肿并病理性骨折，给予骨折切开复位、肿瘤刮除、液氮灭活、自体髂骨及硫酸钙混合植骨、钢板桥接固定骨折。同时，术中取病变组织行病理检查。结果 病理检查诊断为 DF。患者获随访 3 年，术后 5 个月骨折愈合，随访期间无肿瘤复发或转移。结论 股骨中段 DF 临床罕见，临床症状及影像学表现缺乏特异性，应注意与其他骨肿瘤等相鉴别。目前 DF 治疗方法缺少统一标准，局部肿瘤刮除联合液氮处理可能作为一种治疗方法，但需要进一步随访。
Citation：
向超, 陈骞, 柏翰林, 陈路. 股骨中段骨促结缔组织增生性纤维瘤并病理性骨折一例. Chinese Journal of Reparative and Reconstructive Surgery, 2019, 33(1): 129-130. doi: 10.7507/1002-1892.201809102
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- 1. Böhm P, Kröber S, Greschniok A, et al. Desmoplastic fibroma of the bone. A report of two patients, review of the literature, and therapeutic implications. Cancer, 1996, 78(5): 1011-1023.
- 2. Gebhardt MC, Campbell CJ, Schiller AL, et al. Desmoplastic fibroma of bone. A report of eight cases and review of the literature. J Bone Joint Surg (Am), 1985, 67(5): 732-747.
- 3. Said-Al-Naief N, Fernandes R, Louis P, et al. Desmoplastic fibroma of the jaw: a case report and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2006, 101(1): 82-94.
- 4. Gao S, Cai Q, Yao W, et al. Desmoplastic (collagenous) fibroma of the femur: A case report and review of the literature. Oncol Lett, 2013, 6(5): 1285-1288.
- 5. Eyesan SU, Kehinde TG, Adesina AS, et al. Desmoplastic fibroma of the ulna bone. Niger Med J, 2015, 56(2): 153-155.
- 6. Evans S, Ramasamy A, Jeys L, et al. Desmoplastic fibroma of bone: A rare bone tumor. J Bone Oncol, 2014, 3(3-4): 77-79.
