Analysis of clinical efficacy and safety of suturesuspension single hole laparoscopic cholecystectomy and traditional laparoscopic cholecystectomy in the treatment of gallbladder disease_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 ZHANG Weidong , JIN Feng , LU Weixin

Department of General Surgery, No.8 People’s Hospital of Tongzhou District, Nantong, Jiangsu 226361, P.R.China;

Corresponding author：

ZHANG Weidong, Email: zzhj321@163.com

Keywords：

gallbladder disease; suturesuspension single hole laparoscopic cholecystectomy; laparoscopic cholecystectomy; curative effect; safety

DOI：

10.7507/1007-9424.201608017

Video：

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Objective To compare the clinical efficacy and safety of suturesuspension single hole laparoscopic cholecystectomy and traditional laparoscopic cholecystectomy (LC) in the treatment of gallbladder disease. Methods A total of 86 cases who got treatment in our hospital from February 2014 to July 2015 were collected prospectively, and then 86 cases were divided into 2 groups: 43 cases of control group underwent LC and 43 cases of experimental group underwent suturesuspension single hole laparoscopic cholecystectomy. Clinical efficacy and safety of the two groups were compared. Results ① Complication. No one suffered from bile duct injury, bile leakage, bile duct stricture, and umbilical hernia; but there were 2 cases suffered from complications in control group, including 1 case of abdominal pain and 1 case of bloating, and the morbidity was 4.65% (2/43). The morbidity of experimental group was 0, there was no significant difference between the 2 groups in the morbidity (P>0.05). During the follow-up period, 1 case suffered from long-term compilation in experimental group, and 2 cases in normal group, there was no significant difference in the long-term complication between the 2 groups (P>0.05). ② Operation and hospitalization. The blood loss and operation time in the experimental group were lower than those of the control group (P<0.05), but there was no significant difference in the hospital stay and hospitalization cost between the 2 groups (P>0.05). ③ Postoperative electrolytes, liver and kidney function. The levels of Na⁺ and K⁺ in the experimental group were higher than those of the control group (P<0.05), and the levels of alanine aminotransferase and aspartate aminotransferase were lower than those of control group (P<0.01), but there was no significant difference in the blood urea nitrogen and serum creatinine between the 2 groups (P>0.05). ④ The recovery of gastrointestinal function after surgery. The anal exhaust time and bowel sounds recovery time in experimental group were shorter than those of the control group (P<0.01). Conclusion Suturesus-pension single hole laparoscopic cholecystectomy in the treatment of gallbladder disease is safe, effective, and minimally invasive, and it has little disturbance on gastrointestinal function and liver function, which is worthy of clinical application.

Citation： ZHANG Weidong, JIN Feng, LU Weixin. Analysis of clinical efficacy and safety of suturesuspension single hole laparoscopic cholecystectomy and traditional laparoscopic cholecystectomy in the treatment of gallbladder disease. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2017, 24(3): 312-316. doi: 10.7507/1007-9424.201608017 Copy

1.	胡海, 朱江帆, 所广军, 等. 新型经脐入路腹腔镜胆囊切除术. 腹腔镜外科杂志, 2008, 13(2): 145-147.
2.	刘勇, 杨帆, 王雁飞, 等. 25 例经脐单孔腹腔镜胆囊切除术的临床应用体会. 重庆医学, 2014, 43(16): 2056-2058.
3.	Tacchino R, Greco F, Matera D. Single-incision laparoscopic cholecystectomy: surgery without a visible scar. Surg Endosc, 2009, 23(4): 896-899.
4.	秦鸣放, 赵宏志. 肝内外胆管结石的微创治疗. 腹腔镜外科杂志, 2012, 17(3): 166-168.
5.	Rao PP, Bhagwat SM, Rane A,et al. The feasibility of single port laparoscopic cholecystectomy: a pilot study of 20 cases. HPB (Oxford), 2008, 10(5): 336-340.
6.	刘南, 张光永, 胡三元. 悬吊式经脐单孔腹腔镜胆囊切除术与传统腹腔镜胆囊切除术的对比研究. 腹腔镜外科杂志, 2011, 16(2): 96-99.
7.	张忠涛, 韩威, 李建设, 等. 经脐单孔腹腔镜胆囊切除术 1 例报告. 腹腔镜外科杂志, 2008, 13(4): 314.
8.	冯琦. 经脐单孔腹腔镜胆囊切除术治疗急性胆囊炎疗效观察. 中国现代药物应用, 2016, 10(10): 66-67.
9.	王永坤, 朱江帆. 虚拟内镜技术在消化系统疾病诊断中的应用. 中国微创外科杂志, 2010, 10(3): 278-280.
10.	李祺. 针刺穿线胆囊悬吊在经脐单孔腹腔镜胆囊切除术中的临床对照研究. 中国医疗前沿, 2012, 7(19): 3-4, 54.
11.	胡昆鹏, 姚志成, 黄品助, 等. 单孔腹腔镜胆囊切除术 (附视频). 中华肝脏外科手术学电子杂志, 2014, 3(4): 55-56.
12.	蒋泽生, 程远, 徐小平, 等. 吊线法与三器械法单孔腹腔镜胆囊切除术比较. 中华医学杂志, 2013, 93(6): 455-458.
13.	李述剑. 经脐单孔腹腔镜胆囊切除术的安全性及可行性. 中外医学研究, 2016, 14(23): 126-128.
14.	徐献忠, 丁建忠, 孙胜利, 等. 单孔腹腔镜 (完全经脐) 下胆囊切除术 25 例临床报告. 中外医学研究, 2016, 14(10): 93-94.
15.	张祺, 贺长林. 单孔法腹腔镜技术在胆囊切除术中的临床研究. 中国现代医生, 2016, 54(21): 39-41.
16.	王强, 贾新能, 王志敏, 等. 经脐单孔与传统三孔腹腔镜胆囊切除术的临床疗效比较. 浙江医学, 2016, 38(1): 22-25.
17.	马君, 王元宇, 牟一平. 经脐单孔腹腔镜与普通腹腔镜胆囊切除术后脐部感染的分析. 浙江临床医学, 2016, 18(10): 1841-1842.
18.	郑凯欣, 许锐锐, 韩慧, 等. 单孔与多孔腹腔镜胆囊切除术的安全性 Meta 分析. 中华腔镜外科杂志(电子版), 2016, 9(3): 146-151.
19.	李欣, 侯纯升, 白洋, 等. 单孔腹腔镜胆囊切除术的学习曲线: 累积求和分析法. 中国微创外科杂志, 2016, 16(3): 241-244.
20.	张雁凯, 宫轲, 张成才, 等. 腹腔镜胆囊切除术后患者血液高凝状态的危险因素分析. 中国医药, 2016, 11(2): 250-254.
21.	顾炯, 孙爱学, 魏晓明, 等. 腹腔镜脾切除术在乙肝后肝硬化门静脉高压症脾肿大患者中的应用. 中华肝脏外科手术学电子杂志, 2016, 5(5): 308-310.
22.	张宪光, 程远, 蒋泽生, 等. 单孔腹腔镜技术治疗急性胆囊炎 30 例. 中华肝胆外科杂志, 2016, 22(3): 202-203.
23.	Navarra G, La Malfa G, Bartolotta G,et al. The invisible cholecystectomy: a different way. Surg Endosc, 2008, 22(9): 2103.
24.	郭见光, 黄玉芹, 李欣, 等. 经脐单孔腹腔镜手术治疗急性胆囊炎的疗效分析. 中国卫生标准管理, 2016, 7(12): 80-82.
25.	贾鹏松. 经脐单孔腹腔镜胆囊切除术的效果及对患者血管内皮功能和炎症因子的影响. 中国卫生标准管理, 2016, 7(12): 45-46.

1. 胡海, 朱江帆, 所广军, 等. 新型经脐入路腹腔镜胆囊切除术. 腹腔镜外科杂志, 2008, 13(2): 145-147.
2. 刘勇, 杨帆, 王雁飞, 等. 25 例经脐单孔腹腔镜胆囊切除术的临床应用体会. 重庆医学, 2014, 43(16): 2056-2058.
3. Tacchino R, Greco F, Matera D. Single-incision laparoscopic cholecystectomy: surgery without a visible scar. Surg Endosc, 2009, 23(4): 896-899.
4. 秦鸣放, 赵宏志. 肝内外胆管结石的微创治疗. 腹腔镜外科杂志, 2012, 17(3): 166-168.
5. Rao PP, Bhagwat SM, Rane A,et al. The feasibility of single port laparoscopic cholecystectomy: a pilot study of 20 cases. HPB (Oxford), 2008, 10(5): 336-340.
6. 刘南, 张光永, 胡三元. 悬吊式经脐单孔腹腔镜胆囊切除术与传统腹腔镜胆囊切除术的对比研究. 腹腔镜外科杂志, 2011, 16(2): 96-99.
7. 张忠涛, 韩威, 李建设, 等. 经脐单孔腹腔镜胆囊切除术 1 例报告. 腹腔镜外科杂志, 2008, 13(4): 314.
8. 冯琦. 经脐单孔腹腔镜胆囊切除术治疗急性胆囊炎疗效观察. 中国现代药物应用, 2016, 10(10): 66-67.
9. 王永坤, 朱江帆. 虚拟内镜技术在消化系统疾病诊断中的应用. 中国微创外科杂志, 2010, 10(3): 278-280.
10. 李祺. 针刺穿线胆囊悬吊在经脐单孔腹腔镜胆囊切除术中的临床对照研究. 中国医疗前沿, 2012, 7(19): 3-4, 54.
11. 胡昆鹏, 姚志成, 黄品助, 等. 单孔腹腔镜胆囊切除术 (附视频). 中华肝脏外科手术学电子杂志, 2014, 3(4): 55-56.
12. 蒋泽生, 程远, 徐小平, 等. 吊线法与三器械法单孔腹腔镜胆囊切除术比较. 中华医学杂志, 2013, 93(6): 455-458.
13. 李述剑. 经脐单孔腹腔镜胆囊切除术的安全性及可行性. 中外医学研究, 2016, 14(23): 126-128.
14. 徐献忠, 丁建忠, 孙胜利, 等. 单孔腹腔镜 (完全经脐) 下胆囊切除术 25 例临床报告. 中外医学研究, 2016, 14(10): 93-94.
15. 张祺, 贺长林. 单孔法腹腔镜技术在胆囊切除术中的临床研究. 中国现代医生, 2016, 54(21): 39-41.
16. 王强, 贾新能, 王志敏, 等. 经脐单孔与传统三孔腹腔镜胆囊切除术的临床疗效比较. 浙江医学, 2016, 38(1): 22-25.
17. 马君, 王元宇, 牟一平. 经脐单孔腹腔镜与普通腹腔镜胆囊切除术后脐部感染的分析. 浙江临床医学, 2016, 18(10): 1841-1842.
18. 郑凯欣, 许锐锐, 韩慧, 等. 单孔与多孔腹腔镜胆囊切除术的安全性 Meta 分析. 中华腔镜外科杂志(电子版), 2016, 9(3): 146-151.
19. 李欣, 侯纯升, 白洋, 等. 单孔腹腔镜胆囊切除术的学习曲线: 累积求和分析法. 中国微创外科杂志, 2016, 16(3): 241-244.
20. 张雁凯, 宫轲, 张成才, 等. 腹腔镜胆囊切除术后患者血液高凝状态的危险因素分析. 中国医药, 2016, 11(2): 250-254.
21. 顾炯, 孙爱学, 魏晓明, 等. 腹腔镜脾切除术在乙肝后肝硬化门静脉高压症脾肿大患者中的应用. 中华肝脏外科手术学电子杂志, 2016, 5(5): 308-310.
22. 张宪光, 程远, 蒋泽生, 等. 单孔腹腔镜技术治疗急性胆囊炎 30 例. 中华肝胆外科杂志, 2016, 22(3): 202-203.
23. Navarra G, La Malfa G, Bartolotta G,et al. The invisible cholecystectomy: a different way. Surg Endosc, 2008, 22(9): 2103.
24. 郭见光, 黄玉芹, 李欣, 等. 经脐单孔腹腔镜手术治疗急性胆囊炎的疗效分析. 中国卫生标准管理, 2016, 7(12): 80-82.
25. 贾鹏松. 经脐单孔腹腔镜胆囊切除术的效果及对患者血管内皮功能和炎症因子的影响. 中国卫生标准管理, 2016, 7(12): 45-46.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Analysis of clinical efficacy and safety of suturesuspension single hole laparoscopic cholecystectomy and traditional laparoscopic cholecystectomy in the treatment of gallbladder disease

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