Analysis of surgical intervention patterns for newly diagnosed colorectal cancer: a population-based study in Sichuan Province, 2020–2023_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

WANG Liya ¹ , TAN Kun ² , SHEN Minghui ² ,  WANG Xiaodong ¹

1. Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
2. Health Information Center of Sichuan Province, Chengdu 610041, P. R. China;

Corresponding author：

WANG Xiaodong, Email: wangxiaodong@wchscu.cn

Keywords：

colorectal cancer; surgical intervention pattern; surgery rate; Sichuan Province

DOI：

10.7507/1007-9424.202506137

Video：

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Objective To analyze the surgical treatment characteristics for newly diagnosed colorectal cancer (CRC) patients based on hospital registry data in Sichuan Province. Methods Based on the hospitalization records of CRC inpatients from all secondary and tertiary hospitals in Sichuan Province (2015–2024), the newly diagnosed CRC patients admitted during 2020–2023 were identified and the rates of primary lesion resection, neostomy, and stoma reversal procedures were evaluated. Then stratified analyses by gender, age, tumor location, and organ metastasis at diagnosis were analyzed. The statistical significance was defined as one-sided test with α=0.025. Results A total of 118 787 newly diagnosed CRC inpatients in Sichuan Province (2020–2023) were enrolled, the cohort had a mean age of (66.4±12.3) years, with 70 756 (59.6%) males, 64 646 (54.4%) rectal cancer cases, and 16 418 (13.8%) cases exhibiting synchronous organ metastasis at diagnosis. Within one year post-diagnosis, 84 634 (71.2%) patients underwent primary lesion resection and 26 514 (22.3%) received neostomy procedures, both demonstrating significantly increasing annual trends (χ²_trend=72.2, P<0.001; χ²_trend=70.6, P<0.001) while showing inverse correlations with advancing age (χ²_trend=4 096.0, P<0.001; χ²_trend=56.3, P<0.001). Stratified analyses revealed significantly lower primary lesion resection rates among females vs. males, rectal cancer vs. colon cancer, and organ metastasis vs. non-organ metastasis patients (all P<0.001), whereas neostomy rates were higher in females and rectal cancer patients but lower in organ metastasis cases (all P<0.001). Among 26 514 neostomy patients, 11 288 (42.6%) underwent stoma reversal after a median (interquartile range) interval of 123 (95, 188) d, with 8 187 reversals (72.5%) within 6 months, 2 700 (23.9%) during 6–12 months, and 401 (3.6%) after 12 months. Reversal rates increased temporally (χ²_trend=80.0, P<0.001) but decreased with advancing age (χ²_trend=1 072.3, P<0.001). Conclusion In Sichuan Province, rising trends are observed in the hospitalization burdern of newly diagnosed CRC and rates of primary lesion resection, neostomy, and reversal.

Citation： WANG Liya, TAN Kun, SHEN Minghui, WANG Xiaodong. Analysis of surgical intervention patterns for newly diagnosed colorectal cancer: a population-based study in Sichuan Province, 2020–2023. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2025, 32(8): 991-997. doi: 10.7507/1007-9424.202506137 Copy

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10.	李琳, 李旭, 谭坤, 等. 中美结直肠癌流行病学现状及趋势. 中国普外基础与临床杂志, 2025, 32(6): 694-701.
11.	Siegel RL, Kratzer TB, Giaquinto AN, et al. Cancer statistics, 2025. CA Cancer J Clin, 2025, 75(1): 10-45.
12.	Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2024, 74(3): 229-263.
13.	秦敏晔, 王晓飞, 邱晶, 等. 2008–2020年江苏省张家港市结肠癌发病趋势及发病年龄变化特征分析. 中国慢性病预防与控制, 2025, 33(2): 98-103.
14.	田传鑫, 赵磊. 结直肠癌及结直肠癌肝转移流行病学特点. 中华肿瘤防治杂志, 2021, 28(13): 1033-1038.
15.	梁锌, 刘梦雯, 张丽, 等. 全球部分地区肺癌发病趋势及年龄变化情况分析. 中国肿瘤, 2022, 31(9): 683-692.
16.	刘潇霞, 乔良, 罗玉英, 等. 2018年四川省以医院登记为基础的恶性肿瘤发病情况分析. 中国肿瘤, 2021, 30(6): 429-436.
17.	包凯芳, 陈洁平, 王思嘉, 等. 基于区域信息平台的宁波市2011–2022年结直肠癌发病趋势及年龄-时期-队列分析. 中华肿瘤防治杂志, 2025, 32(9): 553-561.

1. Han B, Zheng R, Zeng H, et al. Cancer incidence and mortality in China, 2022. J Natl Cancer Cent, 2024, 4(1): 47-53.
2. 国家卫生健康委员会医政司, 中华医学会肿瘤学分会. 国家卫生健康委员会中国结直肠癌诊疗规范(2023版). 中华胃肠外科杂志, 2023, 26(6): 505-528.
3. 黄雷, 董秋石, 武爱文. 2024年度结直肠癌治疗研究进展. 肿瘤综合治疗电子杂志, 2025, 11(2): 31-43.
4. 彭义炜, 叶霖. 结直肠癌外科治疗的现状和展望. 中外医药研究, 2024, 3(18): 162-164.
5. 李易津, 李俊. 肠癌肝转移外科治疗的国际进展. 肝胆外科杂志, 2024, 32(3): 230-236.
6. 四川省卫生健康委员会. 四川省卫生健康统计调查制度. 成都: 四川省卫生健康委员会, 2012.
7. 段占祺, 高岚岚, 杨珣, 等. 住院病案首页质量考评平台的设计与应用. 中国卫生质量管理, 2020, 27(3): 40-42.
8. 谭坤, 王利亚, 周德嘉, 等. 2015–2019年四川省结直肠癌住院负担分析: 一项以人群为基础的研究. 中国普外基础与临床杂志, 2021, 28(12): 1559-1564.
9. Qiu H, Wang L, Zhou L, et al. Comorbidity patterns in patients newly diagnosed with colorectal cancer: network-based study. JMIR Public Health Surveill, 2023, 9: e41999. doi: 10.2196/41999.
10. 李琳, 李旭, 谭坤, 等. 中美结直肠癌流行病学现状及趋势. 中国普外基础与临床杂志, 2025, 32(6): 694-701.
11. Siegel RL, Kratzer TB, Giaquinto AN, et al. Cancer statistics, 2025. CA Cancer J Clin, 2025, 75(1): 10-45.
12. Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2024, 74(3): 229-263.
13. 秦敏晔, 王晓飞, 邱晶, 等. 2008–2020年江苏省张家港市结肠癌发病趋势及发病年龄变化特征分析. 中国慢性病预防与控制, 2025, 33(2): 98-103.
14. 田传鑫, 赵磊. 结直肠癌及结直肠癌肝转移流行病学特点. 中华肿瘤防治杂志, 2021, 28(13): 1033-1038.
15. 梁锌, 刘梦雯, 张丽, 等. 全球部分地区肺癌发病趋势及年龄变化情况分析. 中国肿瘤, 2022, 31(9): 683-692.
16. 刘潇霞, 乔良, 罗玉英, 等. 2018年四川省以医院登记为基础的恶性肿瘤发病情况分析. 中国肿瘤, 2021, 30(6): 429-436.
17. 包凯芳, 陈洁平, 王思嘉, 等. 基于区域信息平台的宁波市2011–2022年结直肠癌发病趋势及年龄-时期-队列分析. 中华肿瘤防治杂志, 2025, 32(9): 553-561.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Analysis of surgical intervention patterns for newly diagnosed colorectal cancer: a population-based study in Sichuan Province, 2020–2023

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