Objective To evaluate the correlation between benign prostatic hyperplasia (BPH) and metabolic syndrome (MS).
Methods Total 666 elderly male patients admitted to West China Hospital for routine physical examination in May, 2010 were included in this study. The related laboratory tests of BPH and MS were taken. The correlation among BPH, lower urinary tract Symptoms (LUTS), prostate volume (PV), MS and its component diseases were analyzed.
Results Hypertension was an important risk factor for BPH (OR=1.309, 95%CI 1.033 to 1.661), low HDL-C hyperlipidemia was a risk factor for IPSS scored over 7 points (OR=1.573, 95%CI 0.330 to 0.997), and the score of PV was positively correlated to obesity, hypertension, low HDL-C hyperlipidemia and MS (all P lt;0.05).
Conclusion For the patient with BPH, MS and its component diseases mainly exert their effects on PV changes rather than LUTS.
Citation：
LIN Xiufang,YANG Ming,DONG Birong. Correlation between Benign Prostatic Hyperplasia and Metabolic Syndrome. Chinese Journal of Evidence-Based Medicine, 2012, 12(5): 524-526. doi: 10.7507/1672-2531.20120084
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Copyright © the editorial department of Chinese Journal of Evidence-Based Medicine of West China Medical Publisher. All rights reserved
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Gupta A, Gupta S, Pavuk M, et al. Anthropometric and metabolic factors and risk of benign prostatic hyperplasia: a prospective cohort study of air force veterans. Urology, 2006, 68(6): 1198-1205.
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Park HK, Lee HW, Lee KS, et al. Relationship between lower urinary tract symptoms and metabolic syndrome in a community-based elderly population. Urology, 2008, 72(3): 556-560.
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Temml C, Obermayr R, Marszalek M, et al. Are lower urinary tract symptoms influenced by metabolic syndrome? Urology, 2009, 73(3): 544-548.
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- 1. Kasturi S, Russell S, Mcvary KT. Metabolic syndrome and lower urinary tract symptoms secondary to benign prostatic hyperplasia. Curr Urol Rep, 2006, 7(4): 288-292.
- 2. Dahle SE, Chokkalingam AP, Gao YT, et al. Body size and serum levels of insulin and leptin in relation to the risk of benign prostatic hyperplasia. J Urol, 2002, 168(2): 599-604.
- 3. Hammarsten J, Hogstedt B. Hyperinsulinaemia as a risk factor for developing benign prostatic hyperplasia. Eur Urol, 2001, 39(2): 151-158.
- 4. 中国成人血脂异常防治指南制订联合委员会, 中国成人血脂异常防治指南. 中华心血管病杂志, 2007, 35: 390-419.
- 5. 张祥华, 主编. 中国良性前列腺增生诊断治疗指南2007版. 人民卫生出版社, 2007: 167-205.
- 6. Ozden C, Ozdal OL, Urgancioglu G, et al. The correlation between metabolic syndrome and prostatic growth in patients with benign prostatic hyperplasia. Eur Urol, 2007, 51(1): 199-206.
- 7. Parsons JK, Carter HB, Partin AW, et al. Metabolic factors associated with benign prostatic hyperplasia. J Clin Endocrinol Metab, 2006, 91(7): 2562-2568.
- 8. Gupta A, Gupta S, Pavuk M, et al. Anthropometric and metabolic factors and risk of benign prostatic hyperplasia: a prospective cohort study of air force veterans. Urology, 2006, 68(6): 1198-1205.
- 9. Park HK, Lee HW, Lee KS, et al. Relationship between lower urinary tract symptoms and metabolic syndrome in a community-based elderly population. Urology, 2008, 72(3): 556-560.
- 10. Temml C, Obermayr R, Marszalek M, et al. Are lower urinary tract symptoms influenced by metabolic syndrome? Urology, 2009, 73(3): 544-548.
