ObjectivesTo investigate the prevalence of mycoplasma pneumonia (MP) in the pediatric outpatient department of Shanghai Pudong New District Zhoupu Hospital and its relationship with the concentration of fine particulate matter (PM 2.5) in the air.MethodsPatients with respiratory tract infection, from one month to 15 years old, diagnosed in the pediatric department of Shanghai Pudong New District Zhoupu Hospital from May 2016 to April 2017 were enrolled. Mycoplasma pneumonia antibody was detected by colloidal gold assay, and mycoplasma antibody was detected after 1 week of negative test. PM 2.5 index of the same period was also collected. SAS 9.1.3 software was used for statistical analysis.ResultsA total of 3 862 children were enrolled, of which 947 were positive for MP, with a positive rate of 24.52%. The positive rates of each age group were 10.02% for the one month to one year old group, 23.51% for the 1 to 4 years old group, 31.70% for the 4 to 7 years old group, and 22.81% for the 7 to 15 years old group. The positive rate of each age group had statistically significant difference (χ2=86.120 0, P<0.000 1). The positive rates of spring, summer, autumn, and winter were 25.06%, 20.43%, 19.52 and 33.61%, respectively. The difference was statistically significant (χ2=67.1446, P<0.000 1). Combining the PM 2.5 index in Shanghai Pudong area from May 2016 to April 2017, the positive correlation between PM 2.5 and positive rate of MP was found (r=0.9007, P<0.001).ConclusionsThe positive rate of MP in Shanghai Pudong area is 24.52%, and reach its highest level in the preschool children and in winter. It is positively correlated with the PM 2.5 index as well.
Citation：
FU Peihua, WANG Chaoxin, TAN Chunyu. Prevalence of mycoplasma pneumonia in pediatric outpatient department of Shanghai Pudong New District Zhoupu Hospital and its relationship with PM 2.5. Chinese Journal of Evidence-Based Medicine, 2018, 18(2): 130-133. doi: 10.7507/1672-2531.201705112
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| 1. |
许秋艳, 范丽萍, 陶会, 等. 苏州地区婴幼儿肺炎支原体肺炎住院患儿流行病学及临床特点分析. 中国小儿急救医学, 2017, 24(3): 215-219.
|
| 2. |
王军华, 范承武, 刘胜, 等. 桂林市儿童肺炎支原体感染流行特点及与气候因素相关性研究. 临床儿科杂志, 2013, 31(11): 1038-1041.
|
| 3. |
倪慧萍, 季伟, 陈正荣. 气候因素对于儿童肺炎支原体肺炎的作用研究. 中国医药导刊, 2014, 16(11): 1385-1386.
|
| 4. |
徐迎春. 杭州地区儿童支原体肺炎流行特征与气象因素的相关分析. 杭州: 浙江大学, 2010.
|
| 5. |
郭红波. 苏州地区儿童急性呼吸道感染病原学与气候相关性探讨. 苏州: 苏州大学, 2010.
|
| 6. |
刘文渊. 医院就诊儿童肺炎支原体感染的流行特征及与气象因素的相关性研究. 杭州: 浙江大学, 2015.
|
| 7. |
吴邵芳, 裴立红, 兰岩菊, 等. 肺炎与急性荨麻疹相关性的病例对照研究. 中国循证医学杂志, 2014, 14(6): 659-661.
|
| 8. |
Hou W, Xu XJ, Lei YG, et al. The role of the PM 2.5-associated metals in pathogenesis of child mycoplasma pneumoniae infections: a systematic review. Environ Sci Pollut Res, 2016, 23(4): 10604-10614.
|
| 9. |
Sarnat SE, Winquist A, Schauer JJ, et al. Fine particulate matter components and emergency department visits for cardiovascular and respiratory diseases in the St. Louis, Missouri-Illinois, metropolitan area. Environ Health Perspect, 2015, 123(9): 437-444.
|
| 10. |
Traversi D, Cervella P, Gilli G. Evaluating the genotoxicity of urban PM 2.5 using PCR-based methods in human lung cells and the salmonella TA98 reverse test. Environ Sci Pollut Res Int, 2015, 22(6): 1279-1289.
|
| 11. |
胡雨生. 盐城市 2007–2010 年住院患儿肺炎支原体感染的流行病学特征分析. 苏州: 苏州大学, 2012.
|
| 12. |
Zeng X, Xu X, Zheng X, et al. Heavy metals in PM 2.5 and in blood, and children’s respiratory symptoms and asthma from an e-waste recycling area. Environ Pollut, 2016, 210(11): 346-353.
|
- 1. 许秋艳, 范丽萍, 陶会, 等. 苏州地区婴幼儿肺炎支原体肺炎住院患儿流行病学及临床特点分析. 中国小儿急救医学, 2017, 24(3): 215-219.
- 2. 王军华, 范承武, 刘胜, 等. 桂林市儿童肺炎支原体感染流行特点及与气候因素相关性研究. 临床儿科杂志, 2013, 31(11): 1038-1041.
- 3. 倪慧萍, 季伟, 陈正荣. 气候因素对于儿童肺炎支原体肺炎的作用研究. 中国医药导刊, 2014, 16(11): 1385-1386.
- 4. 徐迎春. 杭州地区儿童支原体肺炎流行特征与气象因素的相关分析. 杭州: 浙江大学, 2010.
- 5. 郭红波. 苏州地区儿童急性呼吸道感染病原学与气候相关性探讨. 苏州: 苏州大学, 2010.
- 6. 刘文渊. 医院就诊儿童肺炎支原体感染的流行特征及与气象因素的相关性研究. 杭州: 浙江大学, 2015.
- 7. 吴邵芳, 裴立红, 兰岩菊, 等. 肺炎与急性荨麻疹相关性的病例对照研究. 中国循证医学杂志, 2014, 14(6): 659-661.
- 8. Hou W, Xu XJ, Lei YG, et al. The role of the PM 2.5-associated metals in pathogenesis of child mycoplasma pneumoniae infections: a systematic review. Environ Sci Pollut Res, 2016, 23(4): 10604-10614.
- 9. Sarnat SE, Winquist A, Schauer JJ, et al. Fine particulate matter components and emergency department visits for cardiovascular and respiratory diseases in the St. Louis, Missouri-Illinois, metropolitan area. Environ Health Perspect, 2015, 123(9): 437-444.
- 10. Traversi D, Cervella P, Gilli G. Evaluating the genotoxicity of urban PM 2.5 using PCR-based methods in human lung cells and the salmonella TA98 reverse test. Environ Sci Pollut Res Int, 2015, 22(6): 1279-1289.
- 11. 胡雨生. 盐城市 2007–2010 年住院患儿肺炎支原体感染的流行病学特征分析. 苏州: 苏州大学, 2012.
- 12. Zeng X, Xu X, Zheng X, et al. Heavy metals in PM 2.5 and in blood, and children’s respiratory symptoms and asthma from an e-waste recycling area. Environ Pollut, 2016, 210(11): 346-353.
