Interpretation and utilization of disease burden assessment indicators_Chinese Journal of Evidence-Based Medicine

Authors：

HU Xiaoye ^1,2,3 , LIANG Shanshan ^1,2,3 , ZHANG Xiaolin ⁴ , WANG Yongsheng ^1,2,3 , CUI Lu ^1,2,3 , HUANG Jiayi ^1,2,3 , LIANG Cui ^1,2,3 , WANG Hanbin ^1,2,3 , NIAN Tao ^1,2,3 ,  YANG Kehu ^1,2,3 ,  LI Xiuxia ^1,2,3

1. Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou 730000, P. R. China;
2. Evidence Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, P. R. China;
3. Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, P. R. China;
4. Imperial College London, London SW7 2AZ, UK;

Corresponding author：

YANG Kehu, Email: yangkh-ebm@lzu.edu.cn; LI Xiuxia, Email: lixiuxia@lzu.edu.cn

Keywords：

Disease burden; DALY; Epidemiology; Public health; Healthy life

DOI：

10.7507/1672-2531.202409025

Video：

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Objective To summarize and categorize the epidemiological evaluation indicators of disease burden, and to explore and analyze the research gaps in the existing evaluation indicators of disease burden. Methods The CNKI, WanFang Data, VIP, CBM, PubMed, Embase, Web of Science and Cochrane Library databases were searched by computer to obtain qualitative studies on evaluation indicators of disease burden. The search time limit was from the establishment of the database to October 2023. CASP was used to evaluate the methodological quality of the included studies, and thematic analysis was used to summarize the evaluation indicators of disease burden by NVivo 12 software. Results A total of 19 studies were included, of which 10 studies were of high quality and 9 studies were of medium quality. The evaluation indicators of disease burden were summarized into two three-level core themes: positive indicators and negative indicators. Five second-level analytic themes were used: disease indicators, life loss indicators, life expectancy indicators, cause removal indicators and health status indicators. Twenty-nine level-1 descriptive themes. Conclusion The evaluation indicators of disease burden have their respective scopes of application and limitations. It is necessary to continue strengthening the construction of a comprehensive evaluation index system for disease burden, so that it is comparable and reliable, can adapt to local calculation weights, and covers both family burden and social burden.

Citation： HU Xiaoye, LIANG Shanshan, ZHANG Xiaolin, WANG Yongsheng, CUI Lu, HUANG Jiayi, LIANG Cui, WANG Hanbin, NIAN Tao, YANG Kehu, LI Xiuxia. Interpretation and utilization of disease burden assessment indicators. Chinese Journal of Evidence-Based Medicine, 2025, 25(1): 118-124. doi: 10.7507/1672-2531.202409025 Copy

1.	Kristjuhan U. Postponing aging and prolonging life expectancy with the knowledge-based economy. Rejuvenation Res, 2012, 15(2): 132-133.
2.	World Health Organization. The world health report. 1997.
3.	李茜瑶, 周莹, 黄辉, 等. 疾病负担研究进展. 中国公共卫生, 2018, 34(5): 777-780.
4.	GBD 2021 Forecasting Collaborators. Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021. Lancet, 2024, 403(10440): 2204-2256.
5.	黄崇斐, 拜争刚, 吴淑婷, 等. 定性系统评价的撰写方法介绍. 中国循证医学杂志, 2015, 15(9): 1106-1111.
6.	文煜, 武振宇. 疾病负担评价指标的实证分析—以伤残调整寿命年为例. 卫生职业教育, 2023, 41(7): 156-160.
7.	黎倩欣, 周智华, 梁珊珊, 等. 大数据技术背景下疾病负担应用分析. 中国循证医学杂志, 2023, 23(3): 351-356.
8.	孙秋芬, 吕筠, 李立明. 期望寿命相关指标的发展和应用. 中华流行病学杂志, 2021, 42(9): 1677-1682.
9.	董惠玲, 吴炳义, 武继磊, 等. 健康预期寿命与伤残调整生命年内在关联与差异. 中国公共卫生, 2020, 36(11): 1645-1650.
10.	苗鑫蕾, 张翔, 孟群. 沙利文法中健康期望寿命的测算指标. 中国卫生统计, 2019, 36(6): 906-908.
11.	周尚成, 陈辉, 易卫兵. 应用伤残调整生命年评价疾病负担的方法学探究. 中国慢性病预防与控制, 2011, 19(3): 320-323.
12.	詹一, 俞敏. 健康期望寿命的计算方法与应用. 疾病监测, 2011, 26(12): 1004-1008.
13.	和沛森, 吴群红, 郝艳华, 等. 全球疾病负担测算指标: 伤残调整生命年的探讨. 中国卫生经济, 2011, 30(10): 78-79.
14.	王建生, 金水高. 去病因健康调整期望寿命—一个新的疾病负担评价指标. 中华预防医学杂志, 2009, 43(8): 655-658.
15.	王书平, 时景璞. 疾病负担评价常用指标及其应用. 辽宁医学杂志, 2007, (5): 321-324.
16.	郭世成, 梁晓峰, 左树岩. 疾病负担研究—失能调整寿命年指标的应用. 中国计划免疫, 2006, (1): 72-75.
17.	贾铁武, 周晓农. 疾病负担(DALY)的评价与应用. 中国寄生虫学与寄生虫病杂志, 2005, (5): 304-308.
18.	王斌, 徐凌中. 衡量疾病负担的新指标—DALY. 中国卫生资源, 2002, (5): 230-231.
19.	庄润森, 王声湧. DALYs及其在疾病负担与成本效果分析中的应用. 广东卫生防疫, 2001, (3): 19-23.
20.	徐凌中, 柳丽华, 王永杰, 等. 效用指标的测量方法及其研究进展. 国外医学(卫生经济分册), 2001, 18(2): 88-92.
21.	谢立, 舒丽萍, 施侣元, 等. 减寿分析评价指标研究进展. 国外医学(社会医学分册), 2000, (2): 58-61.
22.	庞琳, 许群, 金水高. 健康寿命年—一个新的测量疾病负担的指标. 卫生研究, 1999, (2): 63-65.
23.	夏毅, 龚幼龙, 顾杏元, 等. 疾病负担的测量指标—DALY(一). 中国卫生统计, 1998, (3): 53-54.
24.	May AM, Struijk EA, Fransen HP, et al. The impact of a healthy lifestyle on disability-adjusted life years: a prospective cohort study. BMC Med, 2015, 13: 39.
25.	张普洪, 武阳丰, 金水高, 等. 个体失能调整损失年的建立和探讨. 中华预防医学杂志, 2004, (2): 47-50.
26.	Arnesen T, Nord E. The value of DALY life: problems with ethics and validity of disability adjusted life years. BMJ, 1999, 319(7222): 1423-1425.
27.	吕繁. 疾病家庭负担和社会负担研究. 北京: 中国协和医科大学, 2000.

1. Kristjuhan U. Postponing aging and prolonging life expectancy with the knowledge-based economy. Rejuvenation Res, 2012, 15(2): 132-133.
2. World Health Organization. The world health report. 1997.
3. 李茜瑶, 周莹, 黄辉, 等. 疾病负担研究进展. 中国公共卫生, 2018, 34(5): 777-780.
4. GBD 2021 Forecasting Collaborators. Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021. Lancet, 2024, 403(10440): 2204-2256.
5. 黄崇斐, 拜争刚, 吴淑婷, 等. 定性系统评价的撰写方法介绍. 中国循证医学杂志, 2015, 15(9): 1106-1111.
6. 文煜, 武振宇. 疾病负担评价指标的实证分析—以伤残调整寿命年为例. 卫生职业教育, 2023, 41(7): 156-160.
7. 黎倩欣, 周智华, 梁珊珊, 等. 大数据技术背景下疾病负担应用分析. 中国循证医学杂志, 2023, 23(3): 351-356.
8. 孙秋芬, 吕筠, 李立明. 期望寿命相关指标的发展和应用. 中华流行病学杂志, 2021, 42(9): 1677-1682.
9. 董惠玲, 吴炳义, 武继磊, 等. 健康预期寿命与伤残调整生命年内在关联与差异. 中国公共卫生, 2020, 36(11): 1645-1650.
10. 苗鑫蕾, 张翔, 孟群. 沙利文法中健康期望寿命的测算指标. 中国卫生统计, 2019, 36(6): 906-908.
11. 周尚成, 陈辉, 易卫兵. 应用伤残调整生命年评价疾病负担的方法学探究. 中国慢性病预防与控制, 2011, 19(3): 320-323.
12. 詹一, 俞敏. 健康期望寿命的计算方法与应用. 疾病监测, 2011, 26(12): 1004-1008.
13. 和沛森, 吴群红, 郝艳华, 等. 全球疾病负担测算指标: 伤残调整生命年的探讨. 中国卫生经济, 2011, 30(10): 78-79.
14. 王建生, 金水高. 去病因健康调整期望寿命—一个新的疾病负担评价指标. 中华预防医学杂志, 2009, 43(8): 655-658.
15. 王书平, 时景璞. 疾病负担评价常用指标及其应用. 辽宁医学杂志, 2007, (5): 321-324.
16. 郭世成, 梁晓峰, 左树岩. 疾病负担研究—失能调整寿命年指标的应用. 中国计划免疫, 2006, (1): 72-75.
17. 贾铁武, 周晓农. 疾病负担(DALY)的评价与应用. 中国寄生虫学与寄生虫病杂志, 2005, (5): 304-308.
18. 王斌, 徐凌中. 衡量疾病负担的新指标—DALY. 中国卫生资源, 2002, (5): 230-231.
19. 庄润森, 王声湧. DALYs及其在疾病负担与成本效果分析中的应用. 广东卫生防疫, 2001, (3): 19-23.
20. 徐凌中, 柳丽华, 王永杰, 等. 效用指标的测量方法及其研究进展. 国外医学(卫生经济分册), 2001, 18(2): 88-92.
21. 谢立, 舒丽萍, 施侣元, 等. 减寿分析评价指标研究进展. 国外医学(社会医学分册), 2000, (2): 58-61.
22. 庞琳, 许群, 金水高. 健康寿命年—一个新的测量疾病负担的指标. 卫生研究, 1999, (2): 63-65.
23. 夏毅, 龚幼龙, 顾杏元, 等. 疾病负担的测量指标—DALY(一). 中国卫生统计, 1998, (3): 53-54.
24. May AM, Struijk EA, Fransen HP, et al. The impact of a healthy lifestyle on disability-adjusted life years: a prospective cohort study. BMC Med, 2015, 13: 39.
25. 张普洪, 武阳丰, 金水高, 等. 个体失能调整损失年的建立和探讨. 中华预防医学杂志, 2004, (2): 47-50.
26. Arnesen T, Nord E. The value of DALY life: problems with ethics and validity of disability adjusted life years. BMJ, 1999, 319(7222): 1423-1425.
27. 吕繁. 疾病家庭负担和社会负担研究. 北京: 中国协和医科大学, 2000.

Chinese Journal of Evidence-Based Medicine

Interpretation and utilization of disease burden assessment indicators

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