Objective To compare the keyhole approach and traditional craniotomy in the treatment of basal ganglia region hypertension cerebral hemorrhage postoperative epileptic curative effect comparison keyhole approach and traditional craniotomy in the treatment of basal ganglia region the curative effect of hypertensive cerebral hemorrhage postoperative epilepsy.
Methods Collected cases of basal ganglia region admitted in department of neurosurgery our hospital from September 2006 to March 2015, 108 cases of hypertensive cerebral hemorrhage patients, randomly divided into two groups:keyhole approach group (58 cases) and conventional surgery group (50 cases).Two groups of patients with perioperative all use the same management scheme, using statistical methods to analyze clinical data of two groups of patients, such as age, sex, blood loss, postoperative epilepsy, drug efficacy and the incidence of adverse drug reactions, etc.
Results Postoperative follow-up of 2 years, keyhole approach group 12 cases sufferred postoperative seizure, 1 case of patients with status epilepticus, no death occurred; a total of 10 cases of mono-antiepileptic drug(AEDs) therapy effectively, and 7 cases present adverse drug reactions; Traditional surgical postoperative seizures 22 cases, 9 cases occurred status epilepticus, and five died as a result, only five were effective for single therapy, and 15 cases with adverse drug reactions.Statistical results suggest the incidence of postoperative epilepsy, the incidence of severe epilepsy, prognosis, single drug control and adverse drug reactions between the tuo groups have significant difference (P < 0.05).
Conclusion Compared with traditional craniotomy for removal of hematoma, keyhole approach greatly reduce the incidnce of basal ganglia region hypertension cerebral hemorrhage postoperative complications, severe epilepsy and adverse reaction of AEDs.Therefore, keyhole approach in the treatment of basal ganglia region hypertension cerebral hemorrhage is an admirable way of treatment.
Citation:
CHEN Jie, LEI ding. Control study on keyhole approach and traditional craniotomy in the treatment of basal ganglia region hemorrhage postoperative seizure. Journal of Epilepsy, 2017, 3(3): 213-216. doi: 10.7507/2096-0247.20170032
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张晖, 刘国荣, 庞江霞, 中脑卒中后癫痫发作的临床特点和视频脑电图分析.中华老年心脑血管病杂志, 2012, 14(10):1074-1076.
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张光伟, 杨军.脑出血颅内血肿微创清除术后继发癫痫46例临床分析.山东医药, 2009, 49(28):11.
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- 1. 王宪荣, 冯华.实用神经外科基础与临床.北京:人民军医出版社, 2003:512-515.
- 2. 周良辅, 主编. 神经外科学. 上海: 复旦大学出版社, 2001: 799.
- 3. 王忠诚, 主编. 神经外科学. 武汉: 湖北科学技术出版社, 2004: 871-872.
- 4. 杨芝荣.脑梗死继发癫痫.临床神经病学杂志, 1996, 9(5):300-301.
- 5. 秦邵森, 国红, 苏闻.中风后癫痫的临床研究.中国神经免疫学和神经病学杂志, 1996, 3(1):46-48.
- 6. 杨明华.50例中风后即发癫痫的临床分析.脑与神经疾病杂志, 2002, 10(1):56.
- 7. 李玉方, 侯红军, 孟森.脑血管病继发癫痫的临床分析.中国实用神经疾病杂志, 2007, 10(4): 95-96.
- 8. 中华医学会神经外科分会.各类脑血管病的诊断要点.中华神经科杂志, 1996, 29(6):379-380.
- 9. 王学峰, 肖波, 孙红斌.难治性癫痫.上海:上海科学技术出版社, 2002:144.
- 10. 李邦松, 王庆梅.70例脑卒中后癫痫的临床特点分析.安徽医药, 2013, 17(09):1533-1535.
- 11. Faught E, Peters D, Bartolucci A, et a1.Seizures after primary intracerebral hemorrhage.Neurology, 1989, 39(4):1089.
- 12. 张晖, 刘国荣, 庞江霞, 中脑卒中后癫痫发作的临床特点和视频脑电图分析.中华老年心脑血管病杂志, 2012, 14(10):1074-1076.
- 13. 张光伟, 杨军.脑出血颅内血肿微创清除术后继发癫痫46例临床分析.山东医药, 2009, 49(28):11.
- 14. PM FoyG P, Copeland MD, Shaw M.The Incidence of postoperative seizures.Acta Neurochir, 1981, 55(7):253-264.