基于2017版癫痫发作分类框架，国际抗癫痫联盟（International League Against Epilepsy，ILAE）完成了癫痫发作操作性分类标准的更新。本次修订由ILAE执行委员会任命的37人工作组共同完成：通过改良Delphi法（共识阈值设定为超过三分之二的多数）公开征求意见后形成修订方案。该修订方案在ILAE 官网公示征求意见后，执委会任命7名专家组成修订小组对反馈意见进行整合，最终更新的分类标准于2025年4月在Epilepsia上发表。更新后的分类标准延续四大主要发作类别：局灶性、全面性、未知是否为局灶性或全面性和无法分类的发作，共包含4个主要类别和21种具体发作类型，并特别注重非英语语种的术语可译性，旨在为从资源有限地区到高级专科癫痫中心的所有癫痫从业人员建立统一术语体系，并为患者及照护者提供通俗易懂的表述。鉴于癫痫发作分类在癫痫诊断和治疗中的重要作用，本文融合中国癫痫领域专家解读《癫痫发作分类标准更新：国际抗癫痫联盟立场声明》并形成共识，旨在推进该分类标准在我国癫痫领域临床和科研中的应用。
Citation：
高慧, 乐治军, 安东梅, 陈佳妮, 陈蕾, 姜维嘉, 李伟, 朱遂强, 汪昕, 周列民, 姜玉武, 张建国, 邓艳春, 丁美萍, 赵国光, 林卫红, 张国君, 丁玎, 王群, 陈阳美, 任连坤, 王小姗, 栾国明, 秦炯, 廖卫平, 王学峰, 肖波, 王玉平, 王艺, 刘晓燕, 周东. 《癫痫发作分类标准更新：国际抗癫痫联盟立场声明》中国专家解读. Journal of Epilepsy, 2025, 11(4): 310-317. doi: 10.7507/2096-0247.202505003
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Gastaut H. Clinical and electroencephalographical classification of epileptic seizures. Epilepsia, 1970, 11(1): 102-113.
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Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia, 1981, 22(4): 489-501.
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Berg A T, Millichap J J. The 2010 revised classification of seizures and epilepsy. Continuum (Minneapolis, Minn. ), 2013, 19(3 Epilepsy): 571-597.
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Fisher R S, Cross J H, French J A, et al. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia, 2017, 58(4): 522-530.
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中华医学会神经病学分会, 中华医学会神经病学分会脑电图与癫痫学组. 国际抗癫痫联盟痫性发作新分类中国专家解读. 中华神经科杂志, 2019, 52(11): 977-980.
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Berg A T, Berkovic S F, Brodie M J, et al. Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009. Epilepsia, 2010, 51(4): 676-685.
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- 1. Gastaut H. Clinical and electroencephalographical classification of epileptic seizures. Epilepsia, 1970, 11(1): 102-113.
- 2. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia, 1981, 22(4): 489-501.
- 3. Berg A T, Millichap J J. The 2010 revised classification of seizures and epilepsy. Continuum (Minneapolis, Minn. ), 2013, 19(3 Epilepsy): 571-597.
- 4. Fisher R S, Cross J H, French J A, et al. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia, 2017, 58(4): 522-530.
- 5. 中华医学会神经病学分会, 中华医学会神经病学分会脑电图与癫痫学组. 国际抗癫痫联盟痫性发作新分类中国专家解读. 中华神经科杂志, 2019, 52(11): 977-980.
- 6. Berg A T, Berkovic S F, Brodie M J, et al. Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009. Epilepsia, 2010, 51(4): 676-685.
