目的 探讨孤立性纤维性肿瘤的诊断及外科治疗方法。
方法 回顾我院10年来经手术切除并行病理检查确诊为孤立性纤维性肿瘤的病例资料,就其诊断和外科治疗方法进行总结与分析。
结果 共16例次患者,肿瘤分别位于胸腔、腹股沟、后腹膜、外阴、颈部、下肢等部位,无明显特异的临床症状。所有病例均行手术完全切除肿瘤,术后经病理学检查和免疫组化染色检查确诊。对患者定期随访,其中2例分别于术后5年和7年肿瘤复发,2例分别随访3年和5年后失访,2例患者分别于随访的第9个月和16个月因全身多发转移死亡,其余患者仍在随访中。
结论 孤立性纤维性肿瘤大多数病例表现为局部缓慢生长的无痛性肿块,无明显的临床症状,术前诊断较困难,目前仅能依靠术后免疫组化检查确诊,手术切除是最佳的治疗方法。
Citation:
朱磊,林琳,郭大伟,孙文郁,王学范,梁健,姜晓峰. Diagnosis and Surgical Treatment of Solitary Fibrous Tumour. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(1): 99-101. doi:
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Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
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Pak PS, Yanagawa J, Abtin F, et al. Surgical management of endobronchial solitary fibrous tumors [J]. Ann Thorac Surag,2010, 90(2): 659-661.
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Ota H, Kawai H, Yagi N, et al. Successful diagnosis diaphragmatic solitary fibrous tumor of the pleura by preoperative ultrasonography [J]. Gen Thorac Cardiovasc Surg, 2010, 58(9):485-487.
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Insabato L, Siano M, Somma A, et al. Extrapleural solitary fibrous tumor: a clinicopathologic study of 19 cases [J]. Int J Surg Pathol, 2009, 17(3): 250-254.
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14. |
Tam ES, Chen EC, Nijhawan N, et al. Solitary fibrous tumor of the orbit: a case series [J]. Orbit, 2008, 27(6): 426-431.
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Takizawa I, Saito T, Kitamura Y, et al. Primary solitary fibrous tumor (SFT) in the retroperitoneum [J] . Urol Oncol,2008,26(3): 254-259.
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- 1. Insabato L, Siano M, Somma A, et al. Extrapleural solitary fibrous tumor: a clinicopathologic study of 19 cases [J]. In J Surg Pathol, 2009, 17(3): 250-254.
- 2. Suehisa H, Yamashita M, Komori E, et al. Solitary fibrous tumor of the mediastinum [J] . Gen Thorac Cardiovasc Surg,2010, 58(4): 205-208.
- 3. 陈卉娇, 张红英, 李响, 等. 26 例孤立性纤维性肿瘤临床病理及免疫组化特征 [J] . 四川大学学报( 医学版), 2004, 35(5):675-679.
- 4. Cox DP, Daniels T, Jordan RC. Solitary fibrous tumor of the head and neck [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2010, 110(1) : 79-84.
- 5. Yilmaz C, Kabatas S, Ozen OL, et al. Solitary fibrous tumor [J]. J Clin Neurosci, 2009, 16(12): 1578-1581.
- 6. Tanaka M, Sawai H, Okada Y, et al. Malignant solitary fibrous tumor originating from the peritoneum and review of the literature [J] . Med Sci Monit, 2006, 12(10): CS95- CS98.
- 7. Bishop JA, Rekhtman N, Chun J, et al. Malignant solitary fibrous tumor: cytopathologic findings and differential diagnosis [J] . Cancer Cytopathol, 2010, 118(2): 83-89.
- 8. Ambrosini-Spaltro A, Eusebi V. Meningeal hemangiopericytomas and hemangiopericytoma/solitary fibrous tumors of exrtracranial soft tissues: a comparison [J] . Virchows Arch, 2010,456(4): 343-354.
- 9. Mosquera JM, Fletcher CD. Expanding the spectrum of malignant progression in solitary fibrous tumors: a study of 8 cases with a discrete anaplastic component— is this dedifferentiated SFT [J] . Am J Surg Pathol, 2009, 33(9): 1314-1321.
- 10. Bini A, Brandolini J, Davoli F, et al. Solitary fibrous tumor of the pleura: surgery and clinical course in 18 cases [J]. Asian Cardiovasc Thorac Ann, 2009, 17(4): 378-381.
- 11. Pak PS, Yanagawa J, Abtin F, et al. Surgical management of endobronchial solitary fibrous tumors [J]. Ann Thorac Surag,2010, 90(2): 659-661.
- 12. Ota H, Kawai H, Yagi N, et al. Successful diagnosis diaphragmatic solitary fibrous tumor of the pleura by preoperative ultrasonography [J]. Gen Thorac Cardiovasc Surg, 2010, 58(9):485-487.
- 13. Insabato L, Siano M, Somma A, et al. Extrapleural solitary fibrous tumor: a clinicopathologic study of 19 cases [J]. Int J Surg Pathol, 2009, 17(3): 250-254.
- 14. Tam ES, Chen EC, Nijhawan N, et al. Solitary fibrous tumor of the orbit: a case series [J]. Orbit, 2008, 27(6): 426-431.
- 15. Takizawa I, Saito T, Kitamura Y, et al. Primary solitary fibrous tumor (SFT) in the retroperitoneum [J] . Urol Oncol,2008,26(3): 254-259.
- 16. Ito H, Fukuda M, Imamura Y, et al. A malignant solitary fibrous tumor in the retroperitoneum [J] . Int J Clin Oncol, 2008,13(2): 173-175.
- 17. Cranshaw IM, Gikas PD, Fisher C, et al. Clinical outcomes of extra-thoracic solitary fibrous tumors [J]. Eur J Surg Oncol,2009, 35(9): 994-998.