Forty-two patients with duodenal ulcer underwent highly selective vagotomy and mucosal antrectomy (HSV+MA) and were followed up for 3 years. Two weeks, 1 year and 3 year after operation, serum gastrim level and gastric emptying capacity were tested. The results show that he postoperative levels of serum gastrin were lower than the preoperative ones, but wih no significant difference (Ｐ＞0.05). Only a few patients had delayed gastric emptying 2 weeks and 1year after operation,but it returned to normal in 3 years .The authors conclude that HSV+MA is a better operative treatment for duodenal ulcer since it can abolish the factors of postoperative ulcer recurence and perserve the functions of the antrum and the pylorus.
Citation：
Yu Peiwu,Wang Daike,Wen Yayuan,et al. THE EFFECT OF HIGHLY SELECTIVE VAGOTOMY AND MUCOSAL ANTRECTOMY ON SERUM GASTRIN AND GASTRIC EMPTYING. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1995, 2(2): 76-78. doi:
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- 1. 王代科.高度选择性迷走神经切断术的现状和进展.腹部外科，1988；1：81.
- 2. 余佩武，王代科，杨顺兴等.高选迷切加胃窦粘膜切除术治疗十二指肠溃疡.实用外科杂志，1990；10：828.
- 3. Goligher J, Hill G, Kenny T, et al. Proximal gastric vagotomy without drainage for duodenal ulcer: results ofter 5-8 years. Br J Surg, 1978;65:145.
- 4. Herrington JL, Sawyer JL, Scott HW, et al. A twenty-five year experience with vagotomy-antrectomy. Arch Surg, 1973;10:469.
- 5. Friensen SR, Tomita T. Further experience with psuedo-Zollinger-Ellixon syndrome; Its place in the mannagment of neuroendocrine duodenal ulceration. World J Surg, 1973;10:469.
- 6. Busman DC, Brombacher PJ, Munting JDK, et al. Highly selective vagotomy and serum gastrin levels. S G O, 1987;165:397.
- 7. 李为苏，王代科，鄢俊等.高选迷切加胃窦粘膜切除术后胃窦运动功能的实验研究.中华实验外科杂志，1994；16：160.
