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"兰丽珍" 2 results
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Hyperprolactinemia is the common clinical syndrome; the causes of hyperprolactinemia are physiological, pharmacological, and pathological, in which prolactinoma is the most common cause. In drug therapy, dopamine agonists are the first choice, but there are 10%–20% of the patients who are resistant to drug therapy. This paper mainly summarized the causes, treatments, mechanisms of drug resistance, treatment during pregnancy, and progresses in the treatment of prolactinoma, so as to provide some theoretical basis to further research of hyperprolactinemia.
Release date：2018-05-24 02:12
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目的 总结分析慢性嗜酸性粒细胞肺炎（chronic eosinophil pneumonia，CEP）的临床特点，提高临床医生对本病的认识。方法 收集山西医科大学第一医院呼吸与危重症医学科2021年5月—2023年9月收治的4例CEP的临床资料，对其临床特点、诊疗过程进行回顾性分析。结果 4例患者中，男性和女性各2例，年龄为22～52岁。所有患者均有咳嗽症状，其中3例伴有咳痰，1例伴有喘息，平均病程4～6个月就诊。4例患者外周血嗜酸性粒细胞及支气管肺泡灌洗液嗜酸性粒细胞百分比均不同程度升高。胸部CT显示4例患者均存在双肺病变及以外周为主的斑片状实变影。所有患者均给予口服激素治疗半年以上序贯吸入激素治疗，症状均好转，肺部磨玻璃影明显吸收，随访10～32个月均未见复发。结论 CEP临床表现无特异性，治疗不规范易复发，考虑全身糖皮质激素疗程结束后序贯吸入激素治疗可降低复发率。患者管理可参照哮喘慢病管理策略，监测外周血嗜酸性细胞及胸部CT调整用药。
Release date：2025-08-25 05:39
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