Uveal melanoma (UM) is a common type of adult ocular malignancy, and its metastasis potential and prognosis are closely related to tumor stage, histopathological features and genetic molecular markers. Currently, eyeball-preserving radiation therapy, including adhesive radiotherapy and proton beam radiotherapy, has become the preferred method for UM treatment. Despite this, overall survival is low, with about 50% of patients eventually developing distant metastases. Recently, remarkable progress has been made in the field of treatment for metastatic uveal melanoma, especially in the development of new technologies and new drugs. These advances reduce the risk of tumor metastasis and spread while improving the cure rate for patients. Tibenfox is a major breakthrough in the treatment of uveal melanoma. Through these explorations, it is hoped that in the future, early diagnosis of the disease can guide prognosis assessment and implement personalized treatment strategies aimed at protecting patient vision, controlling tumor metastasis, and improving survival.
ObjectiveTo observe the curative effect of temporal orbicularis oculi muscle transposition surgery for senile lower eyelid entropion. MethodsSeventy-eight patients including 93 eyes of senile lower eyelid entropion were treated with temporal orbicularis oculi muscle turn surgical treatment between May 2009 and January 2015. Six months after the operation, the rectification was evaluated. ResultsA total of 67 cases (72 eyes) finished the follow-up observation, among which 49 (51 eyes) had a good effect, 18 (21 eyes) had general effect, and 0 (0 eyes) had poor effect. No patients had such complications as infection or eyelid deformity. All the patients' corneal epithelial cell loss was cured after surgery. The skin of lower eyelid of these 67 cases (72 eyes) were raised to various degrees. ConclusionThe orbicularis oculi muscle temporal transposition surgery for the treatment of senile entropion can fulfill both clinical treatment and aesthetic need, and will prevent recurrence in a certain period.