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find Keyword "文献" 327 results
  • Bibliometrical analysis of domestic and international publications in neuro-ophthalmology

    Purpose To analyze the contents of domestic and inter national public ations in neuro-ophthalmology during the past decade. Methods CBM and Medline were separately searched in 2007, by using Medical subject heading for retrieving Chinese and English language neuro-ophthalmic articles which were published between 1997 and 2006. Results A total of 13052 Englishwritten a rticles available for analysis were contributed from more than 70 countries, mainly from USA, United Kingdom, Japan, Germany, Italy and Canada. The order of frequency was visual cortex(4496/13052,34.4%),optic nerve diseases(3870/13052,29.7%),ocular mo tility disorders(2899/13052,22.2%),visual pathway(1191/13052,9.1%)pupil dis orders(596/13052,5.6%). While a total of 3726 articles were retrieved from CBM, the order of frequency being optic nerve diseases(1854,49.8%),ocular motili ty disorders(excluding strabismus, 1357,36.4%),pupil disorders (242, 6.5%),visual cortex(202, 5.4%), visual pathway(excluding retina, optic nerve, visual cortex, 71). Researchers with diverse specialties contributed to the neuro-ophthalmic publications. Compared with international counterpart, domestic articles relate d to basic researches were much less. Conclusion Neuro-ophtha lmoloy is interdisc iplinary with a wide range of researches and various study hotspots. Domestic basic researches on neuro-ophthalmology remain to be strengthened and improved. (Chin J Ocul Fundus Dis,2008,24:99-102)

    Release date:2016-09-02 05:46 Export PDF Favorites Scan
  • 视网膜母细胞瘤的临床表现和诊断

    视网膜母细胞瘤(RB)是一种好发于3 岁以下儿童的高度恶性眼内肿瘤,其临床表现因就诊时疾病所处的阶段不同而不同。可表现为视网膜感觉层内的透明或半透明病灶; 朦胧可见视网膜血管的白色混浊团块;继发视网膜脱离的视网膜下黄白色肿物等。任何大小的RB均可表现为白瞳症。最常见的假性RB包括永存增生性原始玻璃体、Coats病和眼弓蛔虫病。对可疑RB患儿的正确诊断过程,应包括详细的病史采集、体格检查、 外眼检查、裂隙灯生物显微镜检查、结合巩膜压迫法的双目间接检眼镜检查等。B型超声 和CT检查可显示眼内肿瘤并检测出肿块内可能存在的钙化;MRI通常不能检测出钙化,但对评估视神经、眼眶和脑内是否有转移极具价值;光相干断层扫描可用于对化学药物治疗不敏 感的囊性RB检查以及评估随访患者的黄斑解剖结构。外周血和肿瘤组织的DNA检测分析有助于鉴定患者是否存在种质(germline)突变。对具有13号染色体长臂缺失综合征或其他面部畸形特征的儿童,染色体组型分析有可能早期检测出RB. (中华眼底病杂志,2004,20:67-132)

    Release date:2016-09-02 05:58 Export PDF Favorites Scan
  • Situations and Future Tactics of the Developments of PE and DVT in Southern China

    为了解我国南方地区肺栓塞的现状,通过检索中国医院数字图书馆近9年(1999年~2008年)南方地区正式发表的与肺栓塞和深静脉血栓有关的论文共1288篇,进行了统计分析,发现:1、中国南方地区肺栓塞的发现数量逐年增加,且增幅明显;2、诊断水准达到一定程度的部分南方医院,诊断治疗肺栓塞的数量明显高于其他医院,并不比中国北方同类医院低;3、肺栓塞的漏诊、误诊现象依然普遍存在,提高认知和诊治水准仍然是今后工作的方向。

    Release date:2016-09-08 10:04 Export PDF Favorites Scan
  • The current situation, hotspot, and trend of radical thyroidectomy based on atlas

    ObjectiveTo summarize the development status, hot spots, and trends of radical thyroidectomy for thyroid cancer in recent 10 years by analyzing the data and atlas of the literatures related to radical thyroidectomy.MethodsLiteratures statistics and analysis technique of CiteSpace5.1 software were used to analyze the literatures related to radical resection of thyroid cancer, which were collected in CNKI database from January 1, 2008 to December 30, 2017, in order to obtain the trend of annual publication volume change, author and keyword clustering, and co-occurrence.ResultsFor the annual volume of articles, 148 articles were published from 2014 to 2017, with the authors clustering to6 groups with frequent frequency. Most of the authors were independent authors. The study focused on differentiated thyroid carcinoma, lymph node dissection and endoscopic surgery, recurrent laryngeal nerve injury, postoperative infection, decreased blood calcium, perioperative nursing, and preemptive analgesia. There were 35 keywords with order ≥ 6times, 8 keywords in cluster series, and 13 prominent words in the period from 2008 to 2017.ConclusionsThe literature of radical thyroidectomy developed rapidly from 2014 to 2017. Conducting horizontal joint research, cross-sectoral, cross-disciplinary research, and molecular diagnosis research are the deficiency of current research, and it should become the trend of research development.

    Release date:2019-06-05 04:24 Export PDF Favorites Scan
  • 多灶性脉络膜炎的临床表现与治疗

    多灶性脉络膜炎(multifocal choroiditis, MC)是一种特发性脉络膜视网膜病变,主要侵犯中青年女性。常双眼发病,临床表现有前葡萄膜炎、玻璃体炎,典型眼底表现为散在的脉络膜视网膜病灶, 直径50~350 mu;m。约1/3患者出现黄斑部或视盘周围脉络膜新生血管,导致视力下降。主要鉴别疾病有鸟枪弹样脉络膜视网膜病变、多发性一过性白点综合征(multiple evanescent white dot syndrome, MEWDS)、MC伴视网膜下纤维增生(diffuse subretinal fibrosis, DSF) 、类肉瘤病、结核、梅毒、莱姆病和视网膜外层弓形虫病等。最佳治疗方案尚未统一,Tenon囊下注射和口服糖皮质激素有一定疗效。不靠近中心凹的脉络膜新生血管可行激光光凝治疗。慢性复发性患者可考虑使用免疫抑制剂治疗。 (中华眼底病杂志,2003,19:195-197)

    Release date:2016-09-02 06:00 Export PDF Favorites Scan
  • 曲安奈德玻璃体腔注射的临床应用

    糖皮质激素制剂曲安奈德玻璃体腔内注射对控制视网膜、葡萄膜和视神经的炎症,抑制增生性玻璃体视网膜病变(proliferative vitreoretinopathy, PVR)和视网膜、脉络膜 及虹膜的新生血管形成以及治疗各种病变所 致的黄斑水肿显示出良好的临床效果和较为广泛的应用前景。但对其眼科应用的适应证、剂 型和给药剂量、远期疗效以及副作用还需进一步总结研究,注意防止临床滥用现象的发生。 (中华眼底病杂志,2003,19:201-268)

    Release date:2016-09-02 06:00 Export PDF Favorites Scan
  • 裸小鼠异种移植模型在眼科肿瘤研究中的应用

    裸鼠是遗传性免疫缺陷动物的一种,分为裸大鼠(nude rats)和裸小鼠(nude mice)。异种移植的肿瘤在裸小鼠体内的生长受肿瘤自身的相关特性及裸小鼠体内的因素影响。裸小鼠移植瘤基本保留着原发肿瘤的生物学特性,但也在一定程度上表现出一定的异质性。裸小鼠视网膜母细胞瘤及葡萄膜黑色素瘤移植瘤的建立,为研究这些肿瘤的发病机制以及观察和评估各种治疗方法的效果等方面提供了一个良好的体内动物模型。 (中华眼底病杂志,1998,14:127-129)

    Release date:2016-09-02 06:11 Export PDF Favorites Scan
  • Analysis of Adverse Drug Reaction of Glucoside Tripterygium Total

    目的:减少雷公藤多苷片引起的严重不良反应发生,保证用药安全。方法:通过检索雷公藤多苷片不良反应相关文献,筛选个案或典型病例报告,分析该类不良反应的临床特征。结果:64例个案病例中,不良反应累及器官或系统以血液系统为主、其次为生殖系统、泌尿系统和肝胆系统,大多较轻微,为一过性,停药后对症治疗可以恢复,但长期或大剂量服用可能导致严重的不良反应。结论:雷公藤多苷片所致不良反应与服药时间相关,可累积多个系统,建议根据病情严格控制服药剂量,并且在服药前和服药期间检查血、尿常规和肝肾功能。 

    Release date:2016-09-08 10:04 Export PDF Favorites Scan
  • 激光致脉络膜视网膜静脉吻合形成的影响因素

    激光诱导脉络膜视网膜静脉吻合(chorioretinal venous anastomosis ,CRVA)为治疗视网膜静 脉阻塞(retinal vein occlusion ,RVO)提供了新思路;但其成功率受多种因素影响,现就 激光诱导CRVA术中,激光功率、波长、光斑大小、脉冲时间及视网膜的解剖因素和并发症等 对其成功率的影响作一综述。 (中华眼底病杂志,2001,17:77-78)

    Release date:2016-09-02 06:03 Export PDF Favorites Scan
  • 频域光相干断层扫描分层分析及其在眼科疾病中的应用

    光相干断层扫描(OCT)作为一种快速非侵入性和非接触性的检查技术,能对视网膜的解剖结构进行高分辨率的重建。OCT分层分析是随着高分辨率第四代频域(SD)OCT(SD-OCT)广泛应用衍生出来的研究疾病的新方法,能够确定内界膜到Bruch膜之间不同视网膜结构层面的边界并测量相应层面的视网膜结构厚度或面积。有助于对视网膜病变结构和功能研究深入到更细微层面;对了解相关疾病的发生机制,监测评估及早期诊断将会产生深远的影响。但目前分层分析方法尚不十分成熟,在临床或实验过程中,测量时仍存在一定的误差和局限性。还需要以科学审慎的态度解读SD-OCT分层分析的结果,以便客观正确应用这一技术,推动我们对疾病发生发展过程中不同视网膜层面改变的认识不断深入。

    Release date:2016-09-02 05:22 Export PDF Favorites Scan
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