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find Keyword "新生儿" 149 results
  • Open heart operation on neonates with critical congenital heart disease 推荐 CAJ下载 PDF

    Objective To summarize the experience of open heart operation on neonates with critical and complex congenital heart diseases and evaluate the methods of perioperative management. Methods From May 2001 to January 2003, 12 patients of neonates with congenital heart diseases underwent emergency operation. Their operating ages ranged from 6 to 30 days, the body weights were 2.8 to 4.5 kg. Their diagnoses included D-transposition of the great arteries in 4 cases, ventricular septal defect with atrial septal defect in 5 cases, complete atrioventricular septal defect, obstructed supracardiac total anomalous pulmonary venous drainage and cardiac rhabdomyomas in 1 case respectively. 12 cases were operated under moderate or deep hypothermic cardiopulmonary bypass. Results All cases were observed in ICU for 2-11 days and discharged 7-19 days after operation. The postoperative complications included low cardiac output, mediastinal infection, respiratory distress syndrome, systemic capillary leak syndrome and acute renal failure. All cases were cured and the follow-up (from 6 months to 2 years) showed satisfactory outcome. Conclusion A particular cardiopulmonary bypass and proper perioperative management is very important to ensure the successful outcome. Peritoneal dialysis is an effective and safe method for treating acute renal failure after cardiac operation in neonates.

    Release date:2016-08-30 06:27 Export PDF Favorites Scan
  • Association of Myocardial Enzymes’ Changes with Critical Illness Score in Neonatal Infection

    Objective To evaluate the relationship between the severity of neonatal infection and the activity change of cardiac enzyme. Methods A total of 102 infectious neonates in NICU were evaluated with neonatal serious illness scoring system and then divided into non-critical, critical, and extremely-critical groups. The activity of such serum myocardial enzymes as AST, ALT, LDH, CK, and CKMB was tested in the first 24 hours on admission. Comparison between groups and analyses were conducted. Resultes Myocardial enzyme of the critical and extremely-critical groups was obviously higher than that of the non-critical group (Plt;0.01). Conclusion  The serious illness score of infectious neonates is closely associated with the activity change of myocardial enzyme and the level of serum myocardial enzymes has certain advantages in judging the myocardial injury and the disease severity of neonatal infection.

    Release date:2016-09-07 11:04 Export PDF Favorites Scan
  • Annual result of retinopathy of prematurity screening in Shanghai area

    Objective To investigate the incidence of retinopathy of prematuri ty (ROP) in the area of Shanghai, and to provide the preliminary data for the ev aluation of present criteria for ROP screening. Methods Record s of 289 prematur e infants who had undergone ROP screening from the four NICU in Shanghai between February 2004 and January 2005 were analyzed. Screening criteria included prete rm infants or low birth weight (LBW) infants with BW of 2000g or less. The first examination starts at 4 to 6 weeks chronologic age or 32 weeks post conceptual age. Results In the 289 screened infants, 19 had developed acu te ROP. There we re 3 threshold ROP, 7 prethreshold ROP and 9 developed ROP less than prethreshol d. The incidence of ROP was 6.6%. According to the British recommended guideline s(BWle;1500 g or GAle;31 weeks), only 119 out of 289 needed screening and one ca se of stage 1 ROP was missed; the incidence of ROP was 15.1% (18/119). When lowered sc reening criteria to the American guidelines(BWle;1500g or GAle;28 weeks), t here were only 83 infants needed screening, and we missed 2 stage 1 and 1 prethreshold ROP and the incidence of ROP was 19.3% (16/83). Conclusions The i ncidence of ROP i s 6.6% according to our study. It is lower than other reports and it has somethi ng to do with our present screening guideline. Further epidemiological data are needed to modify the guideline accordingly.

    Release date:2016-09-02 05:46 Export PDF Favorites Scan
  • ABSTRACTSINVESTIGATION OF CONGENITAL DEFORMITY OF HAND IN THE NEWBORNS INSHANGHAI

    In 1984, according to the criteria of the classifieation for congenital hand deformity which wasput out by the International Hand Surgery Committee, we had made an investigation for congenitalhand deformity among 318066 newborns in Shanghai. It was found that the inctdence of a congenitalhand malformation was 0. 0808 percent among the total newborns. The congenital malformation ofthe thumb was 37. 74 percent of all deformities of the hand. According to the statistical analysis, we ...

    Release date:2016-09-01 11:32 Export PDF Favorites Scan
  • Nested Case-control Study of the Relationship between Perinatal Factors and Unconjugated Hyperbilirubinemia in Full-term Neonates

    目的 探讨围产期各种相关因素与高间接胆红素血症发病的关系。 方法 选择2011年1月-5月85例产科出生足月高间接胆红素血症患儿血清总胆红素升高(依据其小时龄)达到全国新生儿学组干预推荐方案光疗标准、且结合胆红素<34 μmol/L,即高间接胆红素血症。同时按同性别同年龄阶段出生抽取85例无高胆红素血症足月儿按1︰1配对作对照组。采用单因素分析和条件logistic回归分析的方法,筛选高间接胆红素血症发病的危险因素。 结果 引起高间接胆红素血症的围生因素包括胎龄、产式、窒息、开奶时间延迟、胎粪排出时间延迟、喂养方式、出血、低血糖、红细胞比容和出生体质量下降。其中引起高间接胆红素血症独立的高危围生因素为胎龄、开奶时间延迟、低血糖、出血、红细胞增多症和出生体质量下降。 结论 临床对具有多种高危围生因素的患儿应提高对其发生高胆红素血症可能的预见性,及早采取预防措施。

    Release date:2016-09-08 09:18 Export PDF Favorites Scan
  • Clinical Analysis of 126 Cases of Preterm Birth

    目的:探讨引起早产的原因和影响预后的因素。方法:对我院126例早产进行回顾性分析。结果:早产发生率为5.0%,胎膜早破(PROM)、妊娠高血压综合征(PIH)是引起早产的主要因素。剖宫产与阴道分娩对早产儿结局无明显差异。破膜时间12h内和12h以上两组间宫内感染发生率差异无统计学意义。结论:早产儿预后与早产病因相关。不同分娩方式对新生儿结局没有影响。

    Release date:2016-09-08 10:04 Export PDF Favorites Scan
  • Screening and risk factors analysis of retinopathy of prematurity in Hubei

    Objective To investigate the incidence and risk factors associated with the development of retinopathy of prematurity (ROP) in Hubei province. MethodsFrom July 2009 to May 2011, 313 premature infants (626 eyes) with gestational age less than 37 weeks were examined by indirect ophthalmoscopy and RetCamⅡ as part of ROP screening.Two hundred infants were male and 113 were female. Their birth weight was from 890 to 3500 grams, with a mean of (1977.37±497.03) grams. Their gestational age was from 26 to 37 weeks, with a mean of (33.13±2.44) week. The infants were divided into ROP group and non-ROP group according to the results of screening. All infants were followed up until retinopathy was stable or received laser therapy as the requirements of prevention and control guidelines of ROP. The sex, gestational age, birth weight, delivery mode, IVF baby, multiple pregnancy, oxygen therapy, intrauterine hypoxia, eclampsia, threatened abortion, oxygen history of infants, respiratory distress syndrome, hypoxicischemic encephalopathy, jaundice, and blueray radiation therapy in two groups were statistically analyzed. ResultsIn 313 infants (626 eyes), ROP developed in 52 infants (16.61%) and 87 eyes (13.90%), which including 2 eyes suffering from AP-ROP, 38 eyes from stage 1, 36 eyes from stage 2, 11 eyes from stage 3. There were 261 infants (83.39%) and 539 eyes (8610%) in nonROP group. Eleven infants (20 eyes) received laser therapy. The results of statistical analysis showed that gestation age(t=-4.348), birth weight (t=-3.966), oxygen therapy (χ2=9.05;OR=3.403, 95%CI=1.475 - 7.854) were significantly related to ROP (P<0.05).ConclusionThe incidence of ROP in Hubei province is 16.61%. The gestation age, birth weight and oxygen therapy are closely related to the occurrence of ROP.

    Release date:2016-09-02 05:25 Export PDF Favorites Scan
  • CLINICAL CHARACTERISTICS OF BOCHDALEK HERNIA IN NEONATES AND INFANTS

    Objective To summarize the clinical characteristics, diagnosis and treatment of Bochdalek hernia in neonates and infants. Methods The data of 15 neonates and 10 infants with Bochdalek hernia,undergoing the normal diagnosis and surgical repair from August 1983 to June 2004, were retrospectively reviewed. Location was left in 22 cases and right in 3 cases. Twenty-four cases were treated by operation and 1 case died of respiratory failurebefore operation.Results Before April 1998,7 of 8 (5 neonates,3 infants) cases of Bochdalek hernia stayed healthy and respiratory symptomfree 1 year after operation; they were followed up 1 year and 3 months to 11 years. One premature neonate with Bochdalek hernia died of respiratory failure before operation, and his lung volume was found to be dysplasia. From April 1998 to June 2004, 15(8 neonates,7 infants) of 17 (10 neonates,7 infants)cases of Bochdalek hernia survived postoperatively, while 2 neonates died of respiratory failure. Conclusion The earlier dyspnoea of neonates ofBochdalek hernia occur,the worse their healthy status appear. The standard andtimely surgical repairs could improve the curative ratio. Whether the operationwas suspended depended on the healthy states of babies.

    Release date:2016-09-01 09:23 Export PDF Favorites Scan
  • 新生儿感染聚集性病例调查及流程改进实践

    目的通过新生儿疑似医院感染聚集发病后控制过程回顾,探索有效的控制措施。 方法2013年3月22日-4月1日,通过对一起新生儿疑似医院感染聚集发病事件的现场调查及病原学检测,了解探讨病因线索,提出有效控制措施,包括鼓励报告,不一味责备,管理部门介入,病例调查,环境采样,分组隔离,奶具由消毒供应中心处理,强化手卫生,强化环境消毒,改用小包装无菌棉签,病例讨论等。 结果该新生儿室在短时间内连续发生4例口腔真菌感染患儿,其中2例口腔分泌物涂片见真菌孢子,临床判断为疑似医院感染聚集性病例。经及时采取干预措施,疫情得到了有效改善,未造成不良后果。 结论在临床中,医院感染聚集病例受同源性检测设备昂贵、时间长的限制,常不能及时确诊,该起疑似医院感染聚集病例的调查及处理对类似案例的处置可供借鉴。

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  • The effects of levetiracetam on neonatal safety during early pregnancy: a meta analysis

    ObjectivesUsing systematic literature review to analyze the effects of levetiracetam (LEV) on neonatal safety during early pregnancy.MethodsThe scope of the literature must be English literature, published from 1997 to 2018. Meta-analysis was performed by random effects models.ResultsSeven literatures were included. A total of 672 cases exposed to LEV in treatment group and 772 234 cases in control groups were selected for meta-analysis. There was no significant difference in neonatal malignancy between treatment group and control group[OR=1.05, 95% CI (0.54, 2.02), P=0.37]. Further, we evaluated the effect of LEV monotherapy and polytherapy on neonatal safety, a total of 464 monotherapy cases and 632 polytherapy cases respectively were selected for meta-analysis. The results showed that there was no significant difference between these two therapies in neonatal malignancy [OR=0.54, 95% CI(0.31, 0.96), P=0.32].ConclusionsAs the papers we included, levetiracetam in the treatment of epilepsy during pregnancy is relatively safe for newborn.

    Release date:2018-09-18 10:17 Export PDF Favorites Scan
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