Objective To determine the effectiveness of sodium hyaluronate (SHA) in preventing intraperitoneal (IP) adhesion. Methods Thirty-eight rats were randomly divided into A,B,C groups, normal saline, 6% Dextran-40 or SHA were applied on the present serosal injury respectively, during operation. Biopsy was taken on the 14th postoperative day.Results There were statistically significant differences in the extent of adhesion among three groups (Ｐ＜0.01). Mild inflammatory changes and less fibrous proliferation were found in group C by microscopy and decreased production of collagen (by fibroblast) and active mesothelial cells proliferation were observed in group C under electron microscope. Conclusion SHA appeares to reduce the extent of postoperative IP adhesion, which is more satisfactory than Dextran-40.
【Abstract】Objective To investigate the influent factors on normal intraabdominal pressure （IAP） and establish the IAP regressive equation. Methods The IAPs of 106 hospitalized patients were determined through monitoring the bladder pressures. The relationship between IAP and 14 factors including age, gender, height, weight, body mass index （BMI）, previous and recent abdominal surgical history, reasons for admission，complications and their quantities were analyzed，respectively.Results The mean IAP of the hospitalized patients was 5.5 mm Hg with a range from 0.4 mm Hg to 12.8 mm Hg. The difference among IAPs of different grades of BMIs had statistical significance （F=5.550，P＜0.01）. The male IAPs were 2.0 mm Hg higher than the female IAPs，which had statistical significance （t=3.122，P＜0.01）. The other 12 factors had no significant effects on IAP （Pgt;0.05）. Conclusion Normal IAP is possibly influenced by gender and BMI，and it is individually different.
目的 探讨胆囊切除术时Luschka胆管损伤的诊断及处理。 方法 回顾性分析2 039例胆囊切除术中26例Luschka胆管损伤的情况。 结果 26例中15例于术中发现胆漏点，行缝扎止漏成功，5例行缝扎失败者和3例未找到胆漏点者，经引流后痊愈。术后发现3例，其中1例经鼻胆管引流治愈； 1例经再手术引流治愈； 1例再手术后发生心肌梗塞死亡。 结论 胆囊切除术时Luschka胆管损伤较难避免，术中发现并及时治疗效果最好； 术后发现应及时行剖腹探查和充分引流。