ObjectiveTo evaluate the effect of the timing of surgery on treating refractory epilepsy caused by cavernomas. Method63 patients with refractory epilepsy caused by intracranial supratentorial cavernomas were retrospectively analyzed on the duration of epilepsy, epileptogenesis sitations, and epileptic seizure types. After resection surgeries of cavernomas, the surgical outcomes were compared between the patients with shorter duration of seizures and the longer ones. ResultThe durations of epilepsy were beteen 3 months and 25 years, median 4.5 years. The temporal epilepsies were 43, frontal 12, parietal 3, occipital 1, cingulate gyrus 1, and multiple lobe 3. The overall ILAE class 1 outcome was 71.4% in 63 patients at 2-year-followup, and ILAE class 1 and 2 outcome was 81.6%. The seizure free rate in the group with epilepsy duration shorter than 5 years was 92.1%, better than the 56.0% in the group with epilepsy duration longer than 5 years. ConclusionOnce the diagnosis of medical refractory epilepsy caused by cavernoma was confirmed, the early surgical operation should be considered seriously.
目的 探讨电化学疗法(EChT)对肝海绵状血管瘤(CHL)的治疗价值。方法 应用EChT在剖腹下治疗8例CHL，17个瘤灶。1例合并结节性肝硬变，5例为多发性CHL，14个瘤灶。结果 治疗过程中肝出血量均不超过20 ml。术后无胆漏、腹腔内出血、黄疸、气体栓塞等并发症产生。治疗后随访5～7年，无1例出现瘤灶复发。结论 EChT是治疗CHL的安全而有效的新方法，适合伴有背景肝病的CHL和多发性CHL的治疗，且易于在基层医院推广。
The authors suggest that occlusion of blood flow to the whole liver is not necesarily a routine procedure in surgical removal of giant cavernous hemangioma in the 8th segment of liver. An occlusion tape can be placed around the finferior vena cava inadvance. Separtion of inferior vena cava between the diaphragm and the upper surface of liver sometimes is difficult, so that placement of the tape may fail. The procedure which we performed in four patients was intermittent occlusion of blood flow at the first hepatic hilum at room temperature during dissection and removal of the tumor en bloc. This operative method is simple and safe as compared with that of resection of the 8th segment of liver.
ObjectiveTo explore the clinical features and surgical treatment effects of cavernous angioma in the temporal lobe secondary to epilepsy.Method38 cases of patients with cavernous angioma in the temporal lobe secondary to epilepsy were collected in Department of Neurosurgery of Wuhan Brain Hospital from Jan. 2010 to Jan. 2019. There were 17 males and 21 females, their age range from 8 to 57 years, average (40.05±14.64) years. Their illness duration ranged from 1 to 10 years, average (1.25±2.19) years. The clinical manifestations showed complex partial seizure in 7 cases, partial-secondary-generalized seizure in 8 cases, and generalized tonic-clonic seizure in 23 cases. All the patients underwent CT/MRI and long-term VEEG monitoring examination. Based on their results of clinical manifestations, combined with CT/MRI and VEEG results, all the patients underwent microsurgical cavernous angioma resection under the guidance of ECoG. If necessary, anterior temporal lobectomy or coortical coagulation should be added. The surgical effect were evaluated by Engel levels by followed up.ResultsThe postoperative pathology confirmed the diagnosis of cavernous angioma. The follow-up of 1 ~ 9 years showed the seizure disappeared in 36 cases, and bad effect in 2 cases. The total surgical effect rate was 94.74% (36/38).ConclusionsTo the patients of cavernous angioma in the temporal lobe secondary to epilepsy, the glial scar and hemosiderin sedimentary zone should be resected after resecting the lesion, and if necessary, anterior temporal lobectomy or cortical coagulation could be added. If it is difficult to locate the lesion, neuronavigation and ultrasound can be used, and the postoperative curative result is satisfactory.
【摘要】 目的 探讨治疗肝尾状叶巨大海绵状血管瘤的外科手术方法。方法 通过1 例肝尾状叶巨大海绵状血管瘤外科手术治疗体会并结合文献复习,分析肝尾状叶解剖及影像学特点,探讨外科手术方法。结果 肝尾状叶巨大海绵状血管瘤因肝尾状叶特殊的解剖特点,安全并有效的肝全尾叶血管瘤切除是治疗这类疾病的有效治疗方法。结论 选择合适的手术径路是关键,熟练并精细地解剖、默契的手术配合可以安全切除肝尾状叶巨大海绵状血管瘤。
OBJECTIVE: To discuss clinical application of the color Doppler ultrasonography in diagnosis and treatment of cavernous hemangioma in deep subcutaneous tissue. METHODS: From 1996, 15 cases of cavernous hemangioma were diagnosed and located with color Doppler ultrasonography and were embolized under monitoring of the ultrasonography or resected by operation before re-examination of the hemangioma via the color Doppler ultrasonography after the intervention. RESULTS: Direct embolization was achieved in 10 cases after pinpoint location of the hemangioma by the ultrasonography, and guided embolization was performed successfully in 2 cases via the monitoring of ultrasonography, and operation had to be adopted to remove the focus. No reoccurrence of the hemangioma was observed in all the cases. CONCLUSION: Cavernous hemangioma in deep subcutaneous tissue could be easily diagnosed and located with color Doppler ultrasonography, and could be removed by embolization under monitoring of the ultrasonography successfully.
目的总结肝尾状叶海绵状血管瘤手术切除的指征及技巧。方法对我科2005年9月至2010年9月期间开展的8例肝尾状叶海绵状血管瘤切除病例的临床资料进行分析。结果全组患者均在无血流阻断下顺利完成手术，无手术死亡。术中出血量为1 000～5 000 ml，（2 500±800） ml; 手术时间为3～6 h，(4.2±0.8） h。1例肝硬变患者术后1 d即出现腹水，经积极治疗后得以控制。3例患者术后1周发现右侧胸腔积液，经1～2次胸腔穿刺抽液后治愈。1例患者术后1周出现不全性肠梗阻，经保守治疗1周后痊愈。术后应用B超每半年复查肝脏情况，随访0.5～5年，（2.5±1.2）年，1例失访，1例患者死于心肌梗死，余均存活，仍在随访中。所有病例均未复发。结论肝尾状叶海绵状血管瘤手术应充分显露、精准操作，彻底切除肿瘤，避免大出血和空气栓塞，减少和防止残肝的热缺血再灌注损伤。