There is a great hope to treat long bone defects with bioactive artificial bone constructed by osteoblasts and biomaterials, in which the key point is to provide an optimum environment for the normal function of osteoblasts. The cellular sociological characteristics of osteoblasts were summarized and it was suggested that the ideal bioactive artificial bone should be composed of inorganic and organic materials together with cellular components such as osteoblasts and vascular endothelial cells, and combined with control release of growth factors, following its implantation it could be vascularized very soon and merged with the host bone by bony consolidation.
目的 描述孕妇配偶在妊娠期的焦虑和社会支持现状，并探讨孕妇配偶获得社会支持对其焦虑情绪的影响。 方法 2010年11月－2011年4月，采用焦虑自评量表（SAS）和社会支持评定量表（SSRS） 对105例（回收99例）孕妇配偶进行问卷调查。 结果 孕妇配偶的SAS条目中焦虑及乏力、尿频、多汗等躯体症状得分依次为（1.56 ± 0.58）、（1.62 ± 0.74）、（1.49 ± 0.75）、（2.48 ± 1.18）分，高于国内常模，差异有统计学意义（P＜0.05）；其客观支持、主观支持及社会支持总分依次为（9.48 ± 2.84）、（22.40 ± 3.83）、（7.48 ± 1.83）分，低于国内常模，且差异有统计学意义（P＜0.05）；同时，SAS与客观支持、主观支持、对支持的利用度及社会支持总分呈负相关，r值依次为−0.260、−0.244、−0.094、−0.347，其中SAS与客观支持、主观支持和社会支持总分的相关性有统计学意义（P＜0.05）。 结论 孕妇配偶所获得的社会支持越少，其焦虑程度及出现的躯体化症状越高，作为医务人员，应正确认识孕妇配偶在特殊人生时期存在的心理问题，及时的提供指导，鼓励其表达自己内心的感受，学会利用各种方法来调整自己的心态，并主动扩大其支持系统。同时更应该向家庭、社会提出呼吁，改变传统观念，关注孕妇的同时也要关注孕妇配偶的情感状况。
Comorbidity is a prominent public health problem in the elderly population. To carry out research on the comorbidity of the elderly is not only an important breakthrough to realize the national strategy of actively responding to the aging population, but also a vivid practice of earnestly implementing the "Healthy China" and other action programs. Based on the major public health issues of elderly comorbidity, this paper lists the main contents and methods of elderly comorbidity research from the perspective of secondary research and empirical research, and holds that this field contains both the profound thought of "holistic concept" and the advanced idea of "integrative medicine". At the same time, under the background of the new era, the gradual deepening of the research in this field may give birth to a brand-new discipline - geriatric comorbidity.
ObjectiveTo analyze the 2023 learning society construction project in order to provide references for researchers in this field. MethodsExcel 2021 software was used to summarize and comb the list of key tasks for the construction of a learning society in 2023 (field of higher continuing education) published on the official website of the Chinese Ministry of Education, and to visually analyze the research topics of key tasks in the medical field and the distribution of applicants. ResultsThe analysis found that a total of 250 projects were shortlisted in the cultivation and construction list, including 100 teaching reform and innovation tasks of continuing education for academic degrees, 100 reform and innovation tasks of non-academic education, and 50 tasks to explore the path of coordinated innovation of the three education. The project involved digital transformation, education and teaching reform, ideological and political education, etc. There were 17 medical projects, accounting for 6.8% of the total number of key tasks. The 17 medical key task declaration units were distributed in 12 provinces (regions), which were mainly concentrated in East China, and the construction of "non-double first-class" universities as the main force; The results mainly focused on personnel training and education and teaching reform. ConclusionThe analysis results of the key task list of 2023 learning society construction (field of higher continuing education) provide important references and enlightenment for the researchers in the field of education, and provide guidance and references for the future development of higher continuing education.
目的:研究领悟社会支持对护士生命质量的影响,进一步探讨领悟社会支持的作用,为提高护士身心健康水平提供依据和支持。方法:用WHOQOL-100量表中文版和领悟社会支持量表对我市三所二级甲等医院的499名护士进行问卷调查。结果:①护士生命质量总分较差。②护士领悟社会支持总分处于中等水平。③护士生命质量的各领域与社会支持均呈显著正相关。即社会支持越好,生命质量越高。结论:社会支持与个体心理健康有密切的关系。护士应主动寻求有效的、可利用的社会支持。护理管理人员则应培养护士良好的生理、心理状态和社会适应能力,从而使其生命质量得到提高。
ObjectiveTo investigate the factors that influence Chinese residents, self-rated health and the effects of the multilevel health insurance system and neighborhood social capital on self-rated health. MethodsBased on the 2018 China labor-force dynamics survey data, and Stata 15.0 software was used to conduct χ2 test, univariate analysis and multiple logistic regression model were used to analyze the influencing factors of self-rated health of Chinese residents. An interaction model was used to analyze the interactive effects of the multilevel health insurance system and the social capital of the neighborhood on self-rated health. ResultsA total of 10 201 people were investigated in this study, and 39.20% of them were self-rated unhealthy. After adjusting for confounders, the results of the multivariate logistic regression model showed that having social health insurance (OR=0.8, 95%CI 0.7 to 1.0) and having neighborhood social capital (OR=0.7, 95%CI 0.6 to 0.8) were more inclined to self-rated health. In addition, the results showed that being male, having a college degree or higher, having a job, and drinking alcohol increased the risk of self-rated unhealthy (P<0.05); whereas being 45-59 years of age, 60 years of age or older, in the central and western regions, exercising regularly, and having a disease or injury within two weeks decreased the risk of self-rated unhealthy (P<0.05). There was a positive multiplicative interaction effect between health insurance and neighborhood social capital on residents’ self-rated health (univariate: OR=1.5, 95%CI 1.1 to 3.7, P<0.05; multivariate: OR=1.7, 95%CI 1.2 to 2.4, P<0.05), and negative additive interactions (RERI=−0.8, 95%CI −1.4 to −0.1; AP=−0.3, 95%CI −0.6 to −0.1; SI=0.6, 95%CI 0.5 to 0.8). ConclusionAttention should be paid to the self-rated health status of key populations through means such as health promotion and education, and healthy behavior lifestyles should be promoted. The health insurance system should be further improved, and attention should be paid to the role of social capital in the neighborhood, encouraging residents to actively build a good social neighborhood, and realizing the coordinated development of the multilevel health insurance system and the social capital in the neighborhood.
Objective To investigate the mental health status, perceived social support, as well as the relationship between them among middle school students in Wenchuan Earthquake region, so as to provide references for the relevant department to formulate appropriate strategies and intervention measures. Methods A cluster sampling method was adopted to select all 1698 students (excluded the students in Grade 3) as the research subjects from three middle schools in the disaster regions. All students were investigated with self-designed basic information questionnaire, Symptom CheckList 90 (SCL-90) and Perceived Social Support Scale (PSSS) through self-administered questionnaire. Results The overall positive rate on the SCL-90 was 46.3% among 1690 students, of whom 66.6% had mild psychological problems and 26.5% had moderate to severe psychological problems. The positive rate on the SCL-90 and the score for each factor of SCL-90 were statistically higher in the female students than male students (Plt;0.05). Compared with the senior middle school students, the score on the phobic anxiety subscale of the SCL-90 was statistically higher in the junior middle school students (Plt;0.05), while the score on the obsessive-compulsive subscale was otherwise statistically lower (Plt;0.05). With the exception of the hostility subscale, the score on each subscale of the SCL-90 in the urban students was statistically lower than the rural students (Plt;0.05). The median score on the perceived social support subscale was 60.00, with significant differences between the students of different sexes and grades (Plt;0.05). The overall score on the perceived social support subscale was negatively correlated with the SCL-90 score (r= –0.261, Plt;0.05). The score was negatively correlated with the SCL-90 score in the students regarding different sexes, grades and living areas prior to the earthquake (Plt;0.05). Conclusion The middle school students in the disaster regions have prominent psychological problems; perceived social support is helpful to promote the development of their mental health. In conducting psychological intervention, the difference of individuals’ mental health among different student groups should be concerned, so as to carry out targeted counseling and education.
ObjectiveTo explore the relationship between the natural environment of residential areas and subjective well-being of the elderly and the role of the elderly’s evaluation of the environmental protection work in both. MethodsBased on the China social survey database (CSS) in 2019, Rstudio and Stata software were used to process the data screened according to the restricted conditions, and multi-classification logistic regression analysis and Bootstrap mediation effect test were used to test the effect relationship among variables. ResultsAir pollution, water pollution, noise pollution, land pollution, electromagnetic ionizing radiation pollution and other pollution in residential areas have no direct effect on the subjective well-being of the elderly (P>0.05). The evaluation of the elderly on the environmental protection work had a positive impact on the elderly’s subjective well-being (P<0.01) and played a completely mediating role in the impact of the natural environment in the residential area on the elderly’s subjective well-being. ConclusionThe government should continue to play a leading role in coordinating environmental protection and pollution control work. In addition, establish an open and transparent environmental protection information disclosure system and strengthen communication with the elderly.
ObjectiveTo construct a nomogram prediction model for pain crisis occurrence based on clinical data of patients with advanced non-small cell lung cancer (NSCLC), with the aim of providing a scientific basis for clinical decision-making.MethodsA total of patients with advanced non-small cell lung cancer (NSCLC) admitted to our hospital from January 2022 to January 2024 were selected as the study subjects. Demographic data, disease information, pain severity (assessed using the Numerical Rating Scale, NRS), psychological status (anxiety and depression assessed using the Self-Rating Anxiety Scale, SAS, and the Self-Rating Depression Scale, SDS), and social support (assessed using the Perceived Social Support Scale, PSSS) were collected. Univariate and multivariate Logistic regression analyses were performed to identify independent factors influencing pain crisis. The R software was used to visualize the nomogram, and the Receiver Operating Characteristic (ROC) curve, calibration curve, and Hosmer-Lemeshow test were employed to evaluate the discrimination and calibration of the model.ResultsA total of 500 questionnaires were distributed, and 448 qualified questionnaires were collected, with a qualification rate of 89.6%. The patients were divided into a modeling group (n=314) and a validation group (n=134). Univariate analysis showed significant differences between the pain crisis group and the pain-free group in terms of gender, age, education level, PSSS score, bone metastases, pleural metastases, depression and anxiety levels, and antitumor efficacy (P<0.05). Multivariate Logistic regression analysis showed that bone metastasis, PSSS score, age, depression, and anxiety levels were independent factors influencing pain crisis in patients with advanced NSCLC. Based on the results of the multivariate Logistic regression analysis, a nomogram prediction model for pain crisis occurrence in patients with advanced NSCLC was constructed. The Area Under the Curve (AUC) of the ROC curve in the modeling and validation groups was 0.948 and 0.921, respectively, indicating high discrimination of the model. The calibration curve and Hosmer-Lemeshow test results showed good consistency of the model.ConclusionThis study successfully constructed and validated a nomogram prediction model based on independent factors such as bone metastasis, social support (PSSS score), age, depression, and anxiety levels. This model can objectively and quantitatively predict the risk of pain crisis occurrence in patients with advanced NSCLC, providing a scientific basis for clinical decision-making. It helps identify high-risk patients with pain crisis in advance and optimize pain management strategies, thereby improving patient prognosis and quality of life.
Since the appearance of the concept of evidence-based medicine in 1992, its advanced conception and scientific method has been widely applied in various social science fields, and several sub-disciplines were formed such as evidence-based management, evidence-based education, and evidence-based social work and so on. However, there has been no studies to review its history and condition until now. The purpose of this study was to introduce the evidence-based social science in terms of its origin, development conditions, challenges and strategies. We hope it can serve as reference for research and policy makings in the fields of social science in China.