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find Keyword "精神分裂症" 40 results
  • Contingent Negative Variation in First Episode Deficit and Non-Deficit Schizophrenia: A Comparative Study

    Objective To detect the contingent negative variation (CNV) in first episode deficit and non-deficit schizophrenia and the relationship between CNV and clinical symptoms. Methods Nihon Kohden evoked brain potentials machine were used to measure CNV in 60 patients with non-deficit schizophrenia (NDS), including 50 patients with deficit schizophrenia (DS) and 60 unrelated healthy controls (HC). Click-flashing paradigm was used to record the CNV and the differences among three groups were compared. The clinical status of patients with schizophrenia was determined using the Positive and Negative Syndrome Scale (PANSS). The overall functioning status was assessed using the Global Assessment of Functioning Scale (GAF). Partial correlations were computed to explore associations among the CNV in DS and the clinical data, controlling the sex, age, and education level. Results Compared to HC, both DS and NDS groups showed significantly reduced amplitude of B (F=27.38, P=0.00), significantly delayed reaction time (F=50.30, P=0.00). Compared to HC, the course of PINV in the DS group significantly shortened, while it was significantly delayed in the NDS group (F=15.32, P=0.00). Only in DS, when compared with that in HC, the latency of point A in CNV was delayed (F=61.01, P=0.00). There was no significant difference among three groups in both area of A-S2’ (F=2.34, P=0.10) and area of PINV (F=1.07, P=0.35). Amplitude of B and the course of PINV in the DS group correlated negatively with PANSS subscale of negative symptoms (r= –0.94, –0.89, respectively, Plt;0.05), whereas in the NDS group amplitude of B correlated negatively with PANSS subscale of positive symptoms (r= –0.87, Plt;0.05), but the course of PINV correlated positively with PANSS subscale of positive symptoms (r=0.88, Plt;0.05). Latency of point A in CNV, which was delayed in the DS group, correlated negatively with GAF (r= –0.48, Plt;0.05). Conclusion Generalized abnormalities of CNV existed in DS and NDS, while DS may cause more impairments in CNV than in NDS. The latency of point A in CNV may predict the social function outcomes of DS.

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  • 农娱治疗对慢性精神分裂症患者认知功能恢复作用

    目的 探索农娱治疗对慢性精神分裂症患者认知功能恢复的作用。 方法 对1994年4月-2008年12月收治的80例住院慢性精神分裂症患者随机分为干预组和对照组,对照组给予常规治疗,干预组除常规治疗外,实施自行设计的农娱治疗,治疗时间为6个月,使用韦氏记忆测验(WMS)及威斯康星卡片分类测试(WCST)测评。 结果 两组患者在治疗前WMS、WCST各因子分及总评总和分(指各因子总评分相加)比较,无统计学意义(Pgt;0.05);治疗后对照组与干预组间记忆商数、正确应答数和持续错误数比较均有统计学意义(Plt;0.05)。 结论 农娱治疗可改善慢性精神分裂症患者的认知功能,促进其积极参加人际交往、参与社会生活,在精神分裂症全程治疗中起到了积极作用。

    Release date:2016-09-08 09:47 Export PDF Favorites Scan
  • 精神分裂症合并糖尿病患者的护理干预

    目的 探讨精神分裂症合并糖尿病患者的护理方法与措施。 方法 2011年3月-6月,对21例精神分裂症合并糖尿病患者采取个性化护理措施,控制精神症状、体重、空腹血糖,以促使疾病转归。 结果 患者精神症状和空腹血糖、体重均得到有效控制,患者入院时和出院前平均空腹血糖比较有统计学意义(P<0.05),入院时和出院前平均体重比较无统计学意义(P>0.05),患者住院期间无新的并发症,均获好转或痊愈出院。 结论 通过个性化的护理措施,帮助患者和家属建立良好的生活方式,有效控制患者的空腹血糖和体重,提高其服药依从性;减轻患者的经济负担,提高其生活质量。

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  • 精神分裂症患者全程式康复护理模式的探讨

    目的 探讨精神分裂症患者急性期和恢复期康复训练内容和方法,并探索如何将住院康复和社区康复有机结合。 方法 对2009年6月-2011年8月在精神障碍病房住院治疗的2 132例患者采用开放管理模式,通过制定康复目标,设计康复方案及运用灵活多样的康复训练方法为患者提供康复服务。 结果 灵活多样、轻松愉快的康复训练及开放管理模式,使患者康复训练的依从性大为提高,康复效果明显。 结论 康复训练对改善精神分裂症患者社会功能,提高生活质量有非常重要的作用。与社区医院合作,共同解决出院后患者的后续康复问题,使其得到系统、持续的医疗服务。

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  • Research on Depressive Symptoms of Open Management for Patients with Acute Schizophrenia

    【摘要】 目的 了解全开放管理的急性期精神分裂症患者的抑郁状况,为急性期开放管理提供参考信息。 方法 2009年10-11月,采用卡尔加里精神分裂症抑郁量表(CDSS)对95例精神分裂症患者进行调查。 结果 精神分裂症患者抑郁的发生率为38.95%。且与性别、文化程度、住院次数无关。但与病程密切相关,病程5年以上的患者抑郁状况突出。 结论 精神分裂症患者的抑郁状况明显,需要加强对病情的评估;加强对家属的教育,提高患者的社会支持;早期对患者进行心理干预;以预防自杀的发生。【Abstract】 Objective To find out the depressive situation of patients with schizophrenia in the acute phase under a whole open management, and to provide a scientific basis for the open management. Methods From October to November 2009, 95 patients with schizophrenia were investigated via Calgary depression scale with schizophrenia (CDSS). Results The incidence of depression in patients with schizophrenia was 38.95%, which had no relationship with gender, education level, or frequency of hospitalization. However, the course of the disease was closely related. The depressive symptoms were prominent in patients with the duration more than five years. Conclusion The patients with schizophrenia have obvious depressive symptoms we should. strengthen the evaluation of the disease, improve the family education and the patient′s social support, and implement psychological intervening with patients in the early phase in order to prevent the occurrence of suicide and improve the quality of management.

    Release date:2016-09-08 09:51 Export PDF Favorites Scan
  • Resting-state electroencephalogram classification of patients with schizophrenia or depression

    The clinical manifestations of patients with schizophrenia and patients with depression not only have a certain similarity, but also change with the patient's mood, and thus lead to misdiagnosis in clinical diagnosis. Electroencephalogram (EEG) analysis provides an important reference and objective basis for accurate differentiation and diagnosis between patients with schizophrenia and patients with depression. In order to solve the problem of misdiagnosis between patients with schizophrenia and patients with depression, and to improve the accuracy of the classification and diagnosis of these two diseases, in this study we extracted the resting-state EEG features from 100 patients with depression and 100 patients with schizophrenia, including information entropy, sample entropy and approximate entropy, statistical properties feature and relative power spectral density (rPSD) of each EEG rhythm (δ, θ, α, β). Then feature vectors were formed to classify these two types of patients using the support vector machine (SVM) and the naive Bayes (NB) classifier. Experimental results indicate that: ① The rPSD feature vector P performs the best in classification, achieving an average accuracy of 84.2% and a highest accuracy of 86.3%; ② The accuracy of SVM is obviously better than that of NB; ③ For the rPSD of each rhythm, the β rhythm performs the best with the highest accuracy of 76%; ④ Electrodes with large feature weight are mainly concentrated in the frontal lobe and parietal lobe. The results of this study indicate that the rPSD feature vector P in conjunction with SVM can effectively distinguish depression and schizophrenia, and can also play an auxiliary role in the relevant clinical diagnosis.

    Release date:2020-02-18 09:21 Export PDF Favorites Scan
  • Social Function of Schizophrenic Patients of Different Marriage Status and Breeding Status

    ObjectiveTo compare social function of schizophrenic patients of different marriage status and breeding status. MethodsA total of 218 people diagnosed to have schizophrenia between June and December 2013 were investigated. The research instruments included General Status Questionnaire and Social Disability Screening Scale. ResultsMen had no significant difference in social deficit from women (P>0.05). At the onset of the disease, married male patients were better than single male ones in terms of social function retreating and family function (P<0.05); married female patients were better in all aspects of social function than single female ones (P<0.05); male patients with children were better in family function than those without children (P<0.05); female patients without children had much worse social dysfunction than those with children except in the area of activity outside the family (P<0.05); male patients without children had more obvious social dysfunction than those with children except in such areas as little activity within the family, personal care, external interests and concern (P<0.05); single female patients had worse social dysfunction than married ones at present (P<0.05). ConclusionMarried schizophrenic patients with children have better social function.

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  • Research on the Gender Difference in Patients with Schizophrenia in Communities

    Objective To investigate the difference in first onset age, family history and medication compliance between male and female patients with schizophrenia in communities. Methods We used self-designed questionnaire to survey and analyze 372 cases of schizophrenia between June to August 2014. Results There were no significant differences between male and female schizophrenic patients in the family history, personality before the disease, education level, age, and the onset type and disease course (P > 0.05). The first onset age of male patients [(24.92±8.22) years] was significantly earlier than female patients [(27.02±11.28) years] and the difference was statistically significant (P < 0.05). The number of unmarried male patients (115, 58.97%) was significantly more than unmarried females (81, 45.76%) and the difference was statistically significant (P < 0.05). The full medication compliance rate of female patients (127, 71.75%) was significantly better than that of male patients (115, 58.97%) (P < 0.05). Conclusion The first onset age, marital status and medication compliance are significantly different between the two genders of patients with schizophrenia, which indicates that prevention, treatment and recovery measures for male and female patients should be differentiated.

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  • Influence of Family Care on the Life Quality of Schizophrenic Patients

    ObjectiveTo explore family care and its influence on the life quality of schizophrenia patients. MethodsBetween September 2011 and March 2012, 101 schizophrenia patients were investigated with Questionnaire of Family Care and Quality of Life Inventory and were divided into two groups in order to compare their life quality. According to the scores of Questionnaire of Family Care, 56 subjects were in support group and 45 subjects were in control group. ResultsAmong the 101 patients, 55.45% had good family care and 44.55% had not. In the support group, there was no significant correlation between family care and life quality in the first month and the third month (r=0.023, P=0.894; r=-0.072, P=0.587), while there was a significant correlation between family care and life quality in the sixth month (r=-0.322, P=0.032). In the control group, there was no significant differences in the score of family care and life quality in the first, third and sixth month (r=0.021, P=0.893; r=0.114, P=0.482; r=1.863, P=0.226). ConclusionLong-term family care is significantly correlated with the life quality of schizophrenia patients. If schizophrenic patients get more poor family care, they will have lower life quality. It's important to create a good and comfortable environment for the patients.

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  • 社区精神康复对精神分裂症患者自尊的影响

    目的针对康复期精神分裂症患者进行社区康复训练,探讨社区精神康复对精神分裂症患者自尊的影响。 方法选取2011年3月-9月在四川大学华西医院心理卫生中心住院治疗且达到临床痊愈后出院的精神分裂症患者为研究对象。对照组患者仅进行门诊随访治疗;干预组患者在门诊随访治疗的基础上同时参加由精神科护士和心理咨询师进行的每周1次的社区康复训练课程。再将干预组患者分为5个小组,每个小组11~12例,每天参加1种康复训练,训练时间为1.5~2.0 h。采用自尊量表(SES)对两组患者康复训练前(SES1)、康复训练后3个月(SES2)、康复训练后6个月(SES3)进行评定。 结果将符合入选标准的101例患者随机分为对照组(45例)和干预组(56例)。分别于康复训练前、康复训练后3、6个月发放101份SES,均有效收回,有效回收率为100%。干预组SES1评分[(23.96±2.05)分]与对照组[(23.80±2.61)分]比较差异无统计学意义(P>0.05);干预组SES2、SES3评分[(28.48±2.69)、(33.59±2.33)分]与对照组[(22.29±4.17)、(22.07±4.11)分]比较差异有统计学意义(P<0.05)。 结论社区精神康复训练对提高精神分裂症患者自尊水平有积极意义,可以消除患者的病耻感,预防疾病复发,促使精神患者的心理健康,提高患者的生活质量,使其在社会中找到存在的个人价值感和归宿感。

    Release date:2016-12-27 11:09 Export PDF Favorites Scan
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