Objective To explore the application of fast track surgery (FTS) mode through multidisciplinary cooperation for the perioperative period of liver cancer. Methods A total of 188 patients with liver cancer treated between April and December 2014 were randomly divided into two groups: FTS group (n=94) and control group (n=94). The FTS group was treated with multidisciplinary cooperative FTS mode, while the control group was treated with traditional perioperative treatment. The self-care ability of daily life, pain, ambulation time and frequency, anal exhaust time, defecation time, hospital stay, hospitalization expenses and readmission rate were compared between the two groups. Results Compared with the control group, patients in the FTS group had a better ability of self-care one to three days after surgery, more reduced pain 8, 24 and 48 hours after surgery, more frequent ambulation and longer ambulation time three days after surgery, shorter time of defecation and exhaust, shorter hospital stay and lower hospitalization expenses. All the above differences were statistically significant (P<0.05). The readmission rate, self-care ability four to seven days after surgery, pain scores 72 and 96 hours after surgery were not significantly different (P>0.05). Conclusion Multidisciplinary cooperative FTS mode for liver cancer perioperative rehabilitation can improve patients’ self-care ability, promote a speedy recovery, reduce hospitalization costs, save medical resources and improve disciplinary teamwork ability.
ObjectiveTo explore the continuous care demands in liver transplant recipients and the influencing factors. MethodFrom October to December 2013, 235 liver transplant recipients were investigated with self-designed questionnaire to learn their continuous care demands. Factors affecting demands for continuous care were analyzed with single factor Chi square analysis and binary logistic regression analysis. ResultsA total of 130 recipients (55.3%) needed continuous care. Single factor chi-square analysis showed that three factors including complications, re-hospitalization and time to get to the nearest medical organization were significant for continuous care demands (P<0.05). Binary logistic regression analysis showed that the longer the time spent by liver transplant recipients to reach the nearest medical organization was, the more they hoped for continuous care[OR=3.040, 95%CI (1.585, 5.829), P=0.001]; the patients with readmisson within one year after surgery hoped less continuous care[OR=0.515, 95%CI (0.292, 0.907), P=0.022]. ConclusionsAt present, acceptance degree for continuous care in the liver transplant recipients is quite high. In the continuous care research and practice, we should develop new models and tools to shorten the time and distance between nurses and patients so as to meet the individualized care demands of the patients and improve their quality of life.
Objective To analyze the risk factors associated with fungal infections in adult recipients after living donor liver transplantation (LDLT). Methods Data of 189 recipients from January 2006 to December 2012 who received LDLT at our center were retrospectively analyzed. Cox regression analysis was used to analyze the risk factors for postoperative fungal infections. Results Postoperative fungal infection was found in 12 recipients. The most common infectious site was lung, whereas the most common fungal pathogen was Candida albicans. Multivariate analysis suggested preoperative low albumin level [HR=0.792, 95%CI (0.694, 0.903), P=0.001], massive intraoperative red blood cell transfusion [HR=4.322, 95%CI (1.308, 14.277), P=0.016] and longer postoperative intensive care unit (ICU) stay [HR=3.399, 95%CI (1.004, 11.506), P=0.049] were the independent risk factors for postoperative fungal infections. Conclusions Lung is the most common fungal infection site after LDLT. Preoperative low albumin level, massive intraoperative red blood cell transfusion and longer postoperative ICU contribute to fungal infections after LDLT.
Objective To systematically evaluate effects of enhanced recovery after surgery (ERAS) programme on clinical outcomes of liver resection during perioperative period. Methods The randomized controlled trials (RCTs) of comparing ERAS programme with traditional care programme in patients underwent liver resection were searched by Wanfang, VIP, CNKI, PubMed, Embase, and Cochrane Library databases from inception to January 2016. The quality of the included RCT was assessed independently according to the Cochrane handbook–version 5.1.0 by two reviewers. Meta-analysis was conducted for the eligible RCTs by using RevMan 5.3.0. Results Seven RCTs containing 844 patients were included in this meta-analysis. There were 35 cases of benign tumor, 809 cases of malignant tumor. The ERAS programmes were performed in 415 patients, while the traditional care programmes were performed in 429 patients. Compared with the traditional care programme, the overall complications rate and the Dindo-Clavien grade Ⅰ complications rate were significantly lower〔OR=0.59, 95%CI (0.41, 0.87),P=0.007;OR=0.45, 95%CI (0.27, 0.76),P=0.002〕, the hospital stay and the first anal exhaust time were significantly shorter〔WMD=–2.66, 95%CI (–3.64, –1.69),P<0.000 01;WMD=–20.25, 95%CI (–32.08, –8.42),P=0.000 8〕 in the ERAS programme, but there was no statistically significant difference of the Dindo-Clavien grade Ⅱ–Ⅳ complications rate between these two groups〔OR=0.93, 95%CI (0.53, 1.63),P=0.80〕. Conclusions ERAS is a safe and effective programme in liver resection during perioperative period. Future studies should define active elements to optimize postoperative outcomes for liver resection.
ObjectiveTo investigate status of readiness for hospital discharge of patients with liver cancer after radical surgery and to explore its influencing factors.MethodsA cross-sectional survey was conducted, a total of 200 patients with liver cancer after the radical resection who were planned to discharge within 1 to 2 days in this hospital from January to April 2019 were selected as the study subjects. The general informations and informations relevant readiness for hospital discharge of patients were investigated and analyzed by the questionnaire.ResultsIn this study, 200 questionnaires were distributed, of which 195 were recovered, and 184 were valid, the final effective recovery rate was 92% (184/200). The scores of 4 dimensions of readiness for hospital discharge in 184 patients: The own status was 42.55±12.36, disease knowledge was 51.68±17.58, and response ability was 21.05±6.86, social support available was 31.85±7.56, and the total score of readiness for hospital discharge was 147.07±36.25. One hundred and eighty-four (80.4%) of 184 patients were prepared to discharge. The univariate analysis results showed that the readiness for hospital discharge score was related to the gender, monthly income per household, preoperative comorbidities, and time with tube after the operation (P<0.05); Further the multiple regression analysis showed that the monthly income per household and preoperative comorbidities were the important influencing factors for it (P<0.05).ConclusionsAccording to results of this study on readiness for hospital discharge of patients with liver cancer after operation in this hospital, readiness for hospital discharge is better, and gender, monthly income per household, preoperative comorbidities, and time with tube after operation are influence factors for it, of which monthly income per household and preoperative comorbidities are important influencing factors.
Objective To verify the feasibility and effectiveness of the modified fast-track surgery (FTS) in the perioperative period of open liver resection. Methods A prospective randomized controlled trial was carried out in 188 consecutive patients undergoing open liver resection between March and December 2014 in the Department of Liver Surgery of West China Hospital. The modified fast recovery procedure and standard rehabilitation procedure were compared in terms of length of hospital stay after operation, hospitalization cost, complications and readmission rate. Results A total of 188 consecutive patients were enrolled in the trial. The analysis included 87 patients in the modified fast recovery group and 89 in the standard rehabilitation group. Compared with the standard rehabilitation group, the modified fast recovery group had a shorter length of hospital stay [(5.70±1.47)vs. (7.26±1.96) days] and a lower cost [(42.7±6.7)vs. (47.3±12.5) thousand yuan], and the differences were statistically significant (P<0.05). There were 20 complication cases in the modified group and 39 in the standard group with significant difference (P=0.003). There was no significant difference in the rate of readmission between the two groups (P=1.000). Compared with the standard group, patients in the modified group had less pain 8 hours, the 1st and 2nd days after surgery, better postoperative activities of daily living, more initiative cough times and off-bed activity times, longer duration of movement, and earlier bowel recovery and exhausting, and all the above differences were significantly different (P<0.05). Stepwise regression analysis showed that postoperative complications and bowel recovery and exhausting time were independent related factors for postoperative hospital stay (P<0.001). Conclusions Multimodal analgesia-based fast recovery procedure is feasible and effective in the perioperative period of partial hepatectomy. It can shorten the time of hospitalization and reduce the cost of hospitalization.
目的 调查临床护士对静脉输液治疗相关知识的知晓度，分析存在的问题，以便有针对性地进行专业指导和培训。 方法 2011年8月，自制静脉输液治疗相关知识知晓度的调查问卷，利用护士参加医院集体培训的机会对158名临床护士进行问卷调查。 结果 ① 70.3%的护士静脉输液治疗知识主要来源于医院培训，护士对静脉输液治疗知识的内涵认识欠全面。② 44.2%护士对留置针的规范化固定及冲、封管方法了解不充分，仅约1/3的护士了解留置针A-C-L维护法，规范维护管理知识掌握不充分。③ 护士对静脉输液常见并发症认识欠深入，认为常见并发症发生的主要原因与患者的血管有关（静脉炎占78.5%，渗出占83.5%，导管堵塞占81.0%）。④ 9%的护士发生针刺伤后不能正确处理，护士对针刺伤原因认识清晰，处理方法还需加强培训。 结论 临床护士对静脉输液治疗相关知识的掌握欠全面性、系统性和专业性，需要对护士采取多种形式、多种途径的专业指导和培训，才能使临床护士全面掌握静脉输液治疗相关知识，促进静脉输液治疗规范化和专业化，有效保障护理质量和安全。