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find Keyword "记忆" 88 results
  • Research progress of executive function in temporal lobe epilepsy

    Temporal lobe epilepsy is the most common type of epilepsy in clinic. In recent years, many studies have found that patients with temporal lobe epilepsy have different degrees of influence in executive function related fields. This influence may not only exist in a certain field of executive function, but may be affected in several fields, and may be related to the origin site of seizures. However, up to now, there is no unified standard for the composition of executive function, and it is widely accepted that the three core components of executive function are working memory, inhibitory control and cognitive flexibility/switching. In addition, the International League Against Epilepsy proposed a new definition in 2010, and epilepsy is a brain network disease. There is a close relationship between brain neural network and cognitive impairment. According to the cognitive field, the brain neural network can be divided into six types: default mode network, salience network, executive control network, dorsal attention network, somatic motor network and visual network. In recent years, there has been increasing evidence that four related internal brain networks are series in a range of cognitive processes. The executive dysfunction of temporal lobe epilepsy may be related to the changes of functional connectivity of neural network, and may be related to the left uncinate fasciculus. This article reviews the research progress related to executive function in temporal lobe epilepsy from working memory, inhibitory control and cognitive flexibility, and discusses the correlation between the changes of temporal lobe epilepsy neural network and executive function research.

    Release date:2023-05-04 04:20 Export PDF Favorites Scan
  • Primary study on recognition of vascular stiffness based on wavelet scattering neural network

    Cardiovascular disease is the leading cause of death worldwide, accounting for 48.0% of all deaths in Europe and 34.3% in the United States. Studies have shown that arterial stiffness takes precedence over vascular structural changes and is therefore considered to be an independent predictor of many cardiovascular diseases. At the same time, the characteristics of Korotkoff signal is related to vascular compliance. The purpose of this study is to explore the feasibility of detecting vascular stiffness based on the characteristics of Korotkoff signal. First, the Korotkoff signals of normal and stiff vessels were collected and preprocessed. Then the scattering features of Korotkoff signal were extracted by wavelet scattering network. Next, the long short-term memory (LSTM) network was established as a classification model to classify the normal and stiff vessels according to the scattering features. Finally, the performance of the classification model was evaluated by some parameters, such as accuracy, sensitivity, and specificity. In this study, 97 cases of Korotkoff signal were collected, including 47 cases from normal vessels and 50 cases from stiff vessels, which were divided into training set and test set according to the ratio of 8 : 2. The accuracy, sensitivity and specificity of the final classification model was 86.4%, 92.3% and 77.8%, respectively. At present, non-invasive screening method for vascular stiffness is very limited. The results of this study show that the characteristics of Korotkoff signal are affected by vascular compliance, and it is feasible to use the characteristics of Korotkoff signal to detect vascular stiffness. This study might be providing a new idea for non-invasive detection of vascular stiffness.

    Release date:2023-06-25 02:49 Export PDF Favorites Scan
  • Research on muscle fatigue recognition model based on improved wavelet denoising and long short-term memory

    The automatic recognition technology of muscle fatigue has widespread application in the field of kinesiology and rehabilitation medicine. In this paper, we used surface electromyography (sEMG) to study the recognition of leg muscle fatigue during circuit resistance training. The purpose of this study was to solve the problem that the sEMG signals have a lot of noise interference and the recognition accuracy of the existing muscle fatigue recognition model is not high enough. First, we proposed an improved wavelet threshold function denoising algorithm to denoise the sEMG signal. Then, we build a muscle fatigue state recognition model based on long short-term memory (LSTM), and used the Holdout method to evaluate the performance of the model. Finally, the denoising effect of the improved wavelet threshold function denoising method proposed in this paper was compared with the denoising effect of the traditional wavelet threshold denoising method. We compared the performance of the proposed muscle fatigue recognition model with that of particle swarm optimization support vector machine (PSO-SVM) and convolutional neural network (CNN). The results showed that the new wavelet threshold function had better denoising performance than hard and soft threshold functions. The accuracy of LSTM network model in identifying muscle fatigue was 4.89% and 2.47% higher than that of PSO-SVM and CNN, respectively. The sEMG signal denoising method and muscle fatigue recognition model proposed in this paper have important implications for monitoring muscle fatigue during rehabilitation training and exercise.

    Release date:2022-08-22 03:12 Export PDF Favorites Scan
  • 记忆合金内固定治疗骨折的疗效与存在问题分析

    【摘 要】 目的 总结形状记忆合金接骨器(swan-like memory connector,SMC)内固定的疗效与存在问题。 方 法 2002 年12 月- 2005 年12 月,采用SMC 内固定治疗骨折66 例,男48 例,女18 例;年龄15 ~ 65 岁,平均45 岁。受伤至手术时间5 ~ 10 d,平均5 d。其中肱骨上1/3 骨折5 例、中下1/3 骨折5 例,尺骨上1/3 骨折16 例、下1/3骨折20 例,桡骨骨折6 例,锁骨骨折10 例,髌骨骨折4 例。 结果 患者均获随访,随访时间8 个月~ 3 年,平均1.5 年。X线片示66 例均获骨性愈合,愈合时间为8 个月~ 1 年半。无骨折畸形愈合,无松动、断裂,骨折局部无感染;无神经损伤、肢体疼痛,关节功能障碍等。取出SMC 内固定时间为8 个月~ 3 年。取出SMC 时发生的问题:①骨痂包埋SMC 22 例;②铲除骨痂和SMC 齿周围部分骨皮质,冰水、冰渣不能全部浸透SMC 18 例;③致骨折2 例,骨皮质被SMC 齿压迫处萎缩。 结 论 SMC 治疗骨折手术操作简便、固定牢固,骨折愈合率高,但取出时非常困难,且有导致再骨折的危险。

    Release date:2016-09-01 09:14 Export PDF Favorites Scan
  • THE STUDY ON BIOCOMPATIBILITY OF DIAMONDLIKE CARBON COATED NICKEL-TITANIUM SHAPE MEMORY ALLOY WITH OSTEOBLASTS CULTURED IN VITRO

    Objective To investigate the biocompatibility of diamond-like carbon(DLC) coated NickelTitanium shape memory alloy with osteoblasts cultured invitro. Methods Rabbit’s osteoblasts were incubated with DLCcoated NickelTitanium shape memory alloy disks and uncoated ones of equal size for 5 days. The control group(without shape memory alloy in culture media) was performed simultaneously. The cultured cells were counted and graphed. The samples from culture media were collected and the concentrations of alkaline phosphatase (ALP) and nickel(Ni2+) were measured from the 1st to 5th day respectively. Results The proliferation of osteoblasts and the concentration of ALP in both DLC-coated group and control gruop was higher than uncoated group. The proliferation of osteoblasts on the 3rd, 4th, and 5th day in both DLC-coatedgroup and control group was significantly higher than that in the uncoated group(P<0.05). The concentration of ALP in DLC-coated group on the 2nd, 3rd, and 5th day and in the control group on the 3rd, 4th, and 5th day was significantly higher than that in the uncoated group(P<0.05). The concentration of Ni2+ on the 3rd, 4th, and 5th day was significantly lower than that in the uncoated group(P<0.05). Conclusion DLC- coated NickelTitanium shape memory alloys appears to have better biocompatibility with osteoblast cultured in vitro compared to uncoated ones.

    Release date:2016-09-01 09:24 Export PDF Favorites Scan
  • Prognostic model of small sample critical diseases based on transfer learning

    Aiming at the problem that the small samples of critical disease in clinic may lead to prognostic models with poor performance of overfitting, large prediction error and instability, the long short-term memory transferring algorithm (transLSTM) was proposed. Based on the idea of transfer learning, the algorithm leverages the correlation between diseases to transfer information of different disease prognostic models, constructs the effictive model of target disease of small samples with the aid of large data of related diseases, hence improves the prediction performance and reduces the requirement for target training sample quantity. The transLSTM algorithm firstly uses the related disease samples to pretrain partial model parameters, and then further adjusts the whole network with the target training samples. The testing results on MIMIC-Ⅲ database showed that compared with traditional LSTM classification algorithm, the transLSTM algorithm had 0.02-0.07 higher AUROC and 0.05-0.14 larger AUPRC, while its number of training iterations was only 39%-64% of the traditional algorithm. The results of application on sepsis revealed that the transLSTM model of only 100 training samples had comparable mortality prediction performance to the traditional model of 250 training samples. In small sample situations, the transLSTM algorithm has significant advantages with higher prediciton accuracy and faster training speed. It realizes the application of transfer learning in the prognostic model of critical disease with small samples.

    Release date:2020-04-18 10:01 Export PDF Favorites Scan
  • Tension-Free Repair of Middle and Small Incisional Hernia by Modified Kugel Patch Reports of 25 Cases

    目的 探讨带记忆弹簧圈(MK)补片在无张力修补中、小切口疝中的应用。方法 回顾性分析2005年1月至2007年1月期间我院实施MK补片下置术修补腹壁中、小切口疝25例患者的临床资料,其中初发21例,复发4例。结果 22例一期愈合,3例发生切口皮下积液,经穿刺抽吸处理后治愈。住院7~15 d,均痊愈出院。随访10个月至2年,无复发病例。结论 用MK补片下置术修补腹壁中、小切口疝经济、安全、有效、感染风险降低。

    Release date:2016-09-08 11:05 Export PDF Favorites Scan
  • Shape Memory Alloy Stent for Intestinal Obstruction Due to Rectal Cancer

    Objective To evaluate initial experience with shape memory alloy stent as an alterative to colostomy in patients with intestinal obstruction of rectal cancer. Methods Twenty-one patients with acute and chronic rectal obstructions from malignant causes underwent stent placement. After rectal stent was slenderized in ice water, it was inserted into the strictured rectum by hand or sigmoidoscope. Nitinol mesh stent were deployed in hot water. Results Eighteen patients who had underwent rectal stent placement achieved clinical decompression within 5 hours. Colostomy underwent in 3 patients due to stent failure. Eighteen patients with stent were followed-up, 14 cases died in 56-720 days and 4 other cases were still alive without intestinal obstruction in 2-15 months. Conclusion Nitinol mesh stent may be useful in the management of terminal or high-risk surgical patients for palliative purposes shuning colostomy. Palliation of stent combined with chemotherapy and immunotherapy can be performed to improve survival.

    Release date:2016-08-28 05:10 Export PDF Favorites Scan
  • BIOMECHANICAL EVALUATION OF TiNi SHAPE-MEMORY SAWTOOTH-ARM EMBRACING PLATE AND ITS EFFECT ON FRACTURE HEALING

    Objective  To investigate the detailed biomechanics of TiNi shape-memory sawtooth-arm embracing plate (TiNi SMA) by comparing with l imited-contact dynamic compression plate (LC-DCP) and static interlocking intramedullary nail (SIiN), so as to provide theoretical evidence for cl inical appl ication. Methods  Eight paired cadaveric femurs immersed in formaldehyde were harvested from eight specimens of adults. After making X-ray films and modeling midpiece transverse fracture, one side randomly was fixed by TiNi SMA (group A) and SIiN (group C) orderly, the other side was fixed by LC-DCP (group B). The axial compression, three-point bending (pressed from plate side and opposite side both of group A and group B, from inside of group C), and torsion were tested, and the stress shielding rate was compared.  Results At every classified axial compression load, the strains of group A were greater than those of group B and group C (P lt; 0.05), the displacements of group A were greater than those of group B and group C (P lt; 0.05) except 100 N. At every classified three-point bending moment, the displacement of group A were greater than those of group B and group C pressed both from two sides, but there was no difference when pressing from two sides under the same load of group A (P gt; 0.05). At every torsion moment, the torsion angels of group A were greater than those of group B (P lt; 0.05), but equal to those of group C (P gt; 0.05). At 600 N of axial compression load, the stress shielding rates of groups A, B, C were 48.30% ± 22.99%, 89.21% ± 8.97%, 95.00% ± 3.15%, respectively, group A was significantly less than group B and group C (P lt; 0.01).  Conclusion The anti-bending abil ity of TiNi SMA is weaker than LC-DCP and SIiN; the anti-torsion abil ity of TiNi SMA is weaker than SIiN, but TiNi SMA is a center-type internal fixation, the superior stress shielding rate and micromovement promote the stress stimulation of fracture, which makes it an ideal internal fixation device.

    Release date:2016-08-31 05:47 Export PDF Favorites Scan
  • Two Internal Fixation Methods for Multiple Rib Fractures: A Case Control Study

    目的探讨可吸收肋骨钉与记忆合金接骨板内固定两种方法治疗多发性肋骨骨折的效果。 方法回顾性分析2009年1月至2014年1月在上海市第六人民医院胸外科行手术内固定的胸部外伤致多根多处肋骨骨折患者321例的临床资料,其中可吸收肋骨钉组70例,其中男62例、女8例,年龄(48.54±9.74)岁;记忆合金接骨板组251例,其中男187例、女64例,年龄(51.44±10.22)岁。分析两组患者疗效差异。 结果两组患者术前疼痛评分(7.74±0.89 vs.7.66±0.92)、术后疼痛评分(3.80±0.79 vs.3.82±0.85),术后胸腔引流时间[(6.00±2.84)d vs.(5.68±2.98)d]差异均无统计学意义(P>0.05)。记忆合金接骨板组住院时间[(20.06±7.39)d vs.(17.77±7.68)d],及手术时间(101.29±30.67)min vs.(71.95±29.50)min]均短于可吸收肋骨钉组,且差异有统计学意义(P<0.05)。术后3个月随访复查胸部X线,两组患者骨折再移位差异无统计学意义。 结论可吸收肋骨钉与记忆合金接骨板均是治疗多发性肋骨骨折较理想的术式,记忆合金接骨板手术操作更为简单,可吸收肋骨钉手术无需在体内留置金属内固定装置,但固定强度较接骨板略差,应根据情况选择合适的内固定方法。

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