Objective To explore the impact of anemia on the incidence of perioperative lower limb deep vein thrombosis (DVT) in patients undergoing total hip arthroplasty (THA). Methods A retrospective analysis was conducted on clinical data of 1 916 non-fracture patients who underwent THA between September 2015 and December 2021, meeting the selection criteria. Among them, there were 811 male and 1 105 female patients, aged between 18 and 94 years with an average of 59.2 years. Among the patients, 213 were diagnosed with anemia, while 1 703 were not. Preoperative DVT was observed in 55 patients, while 1 861 patients did not have DVT preoperatively (of which 75 patients developed new-onset DVT postoperatively). Univariate analysis was performed on variables including age, gender, body mass index (BMI), diabetes, hypertension, history of tumors, history of thrombosis, history of smoking, revision surgery, preoperative D-dimer positivity (≥0.5 mg/L), presence of anemia, operation time, intraoperative blood loss, transfusion requirement, and pre- and post-operative levels of red blood cells, hemoglobin, hematocrit, and platelets. Furthermore, logistic regression was utilized for multivariate analysis to identify risk factors associated with DVT formation. Results Univariate analysis showed that age, gender, hypertension, revision surgery, preoperative levels of red blood cells, preoperative hemoglobin, preoperative D-dimer positivity, and anemia were influencing factors for preoperative DVT (P<0.05). Further logistic regression analysis indicated that age (>60 years old), female, preoperative D-dimer positivity, and anemia were risk factors for preoperative DVT (P<0.05). Univariate analysis also revealed that age, female, revision surgery, preoperative D-dimer positivity, anemia, transfusion requirement, postoperative level of red blood cells, and postoperative hemoglobin level were influencing factors for postoperative new-onset DVT (P<0.05). Further logistic regression analysis indicated that age (>60 years old), female, and revision surgery were risk factors for postoperative new-onset DVT (P<0.05). Conclusion The incidence of anemia is higher among patients with preoperative DVT for THA, and anemia is an independent risk factor for preoperative DVT occurrence in THA. While anemia may not be an independent risk factor for THA postoperative new-onset DVT, the incidence of anemia is higher among patients with postoperative new-onset DVT.
ObjectiveTo investigate the correlation between the Barthel index score and other factors before revision total hip arthroplasty (THA) and the incidence of lower extremity deep venous thrombosis (DVT). MethodsThe clinical data of 122 THA revision patients who met the selection criteria between April 2017 and November 2020 were retrospectively analyzed. There were 61 males and 61 females with an average age of 65.3 years ranging from 32 to 85 years. The causes of revision were periprosthetic infection (7 cases), periprosthetic fracture (4 cases), prosthesis dislocation (6 cases), and aseptic loosening (105 cases). The Barthel index score was 76.4±17.7, including 10 cases of grade 1, 57 cases of grade 2, 37 cases of grade 3, and 18 cases of grade 4. Univariate analysis was performed on the age, gender, body mass index, Barthel index score, positive D-dimer, history of diabetes, hypertension, history of tumor, history of cerebral infarction, history of smoking, and history of thrombosis in patients with and without DVT before operation. The risk factors of DVT before revision THA were further screened by logistic regression analysis, and the incidence of DVT before revision THA was compared among different Barthel index grade. ResultsEleven patients (9.02%) were found to have preoperative DVT, all of which were intermuscular venous thrombosis. The causes of revision were periprosthetic infection in 1 case, periprosthetic fracture in 1 case, prosthesis dislocation in 1 case, and aseptic loosening of prosthesis in 8 cases. Univariate analysis showed that there were significant differences in age, gender, and Barthel index score between the two groups (P<0.05). Further logistic regression analysis showed that female, age ≥70 years, and Barthel index score <60 were independent risk factors for DVT before THA revision (P<0.05). Preoperative DVT occurred in 0 (0), 2 (3.5%), 3 (8.1%), and 6 (33.3%) patients with Barthel index grade 1, 2, 3, and 4, respectively. There was a correlation between Barthel index grade and the incidence of DVT before THA revision (P=0.001). ConclusionIn patients undergoing revision THA, older age, female, and lower Barthel index score were associated with a higher incidence of preoperative DVT. For patients with low preoperative Barthel scores, preoperative screening for thrombosis should be emphasized.