Under the trend of “new medical disciplines leading the innovation of medical education”, in order to solve the difficulties in cultivating medical-engineering talents, such as the lack of a systematic talent cultivation system and integrated teaching staff, the School of Allied Health Sciences, West China School of Medicine of Sichuan University leverages the comprehensive strengths of Sichuan University and joins hands with the School of Mechanical Engineering of Sichuan University to set up a double bachelor’s degree program in Medical Technology and Intelligent Manufacturing, and establish a cultivation mode for medical-engineering compound talents by “integrating science-education teams, developing first-class interdisciplinary platforms, compiling medical engineering textbooks, reshaping teaching methods, and configuring tripartite mentors”. This collaboration aims to form a medical technology education system that meets the development requirements of modern medicine, and to promote the development of medical technology toward digitalization, precision, and informatization. This practice provides a reference for the cultivation of medical-engineering compound talents under the trend of new medical disciplines.