Efficacy comparison between continuous renal replacement therapy and intermittent hemodialysis in the treatment of severe acute renal failure_West China Medical Journal

Authors：

 LIU Qiang ¹ , XU Lin ²

1. Intensive Care Unit, the Affiliated Dongnan Hospital of Xiamen University (the 175th Hospital of PLA), Zhangzhou, Fujian 363000, P. R. China;
2. Department of Nephrology, the Affiliated Dongnan Hospital of Xiamen University (the 175th Hospital of PLA), Zhangzhou, Fujian 363000, P. R. China;

Corresponding author：

LIU Qiang, Email: liuqiang10w@163.com

Keywords：

Severe acute renal failure; Continuous renal replacement therapy; Intermittent hemodialysis therapy; Survival rate

DOI：

10.7507/1002-0179.201512213

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To compare the clinical effect of continuous renal replacement therapy (CRRT) and intermittent hemodialysis (IHD) in the treatment of severe acute renal failure (ARF). Methods A hundred patients with severe ARF treated between May 2011 and December 2014 were chosen to be the study subjects. According to the order of admission, they were divided into control group and observation group with 50 patients in each. Patients of the control group underwent IHD, while those in the observation group underwent CRRT. Serum creatinine (Scr), blood urea nitrogen (BUN), endogenous creatinine clearance rate (Ccr), treatment effective rate and survival rate were compared between the two groups before and after the treatment. Results Scr, BUN and Ccr were all improved after treatment in both the two groups. However, Scr, BUN and Ccr in the observation group [(225.1±162.7) μmol/L, (14.2±9.3) mmol/L, (23.4±10.5) mL/min] were significantly better than those in the control group [(588.4±183.6) μmol/L, (29.1±10.4) mmol/L, (15.9±8.2) mL/min]. The treatment effective rate and patients’ survival rate in the observation group were respectively 60% and 70%, both significantly higher than those in the control group (40% and 52%) All the differences were significant (P<0.05). Conclusion CRRT is superior in the treatment of severe ARF with a higher survival rate of the patients, which is worthy of clinical promotion.

Citation： LIU Qiang, XU Lin. Efficacy comparison between continuous renal replacement therapy and intermittent hemodialysis in the treatment of severe acute renal failure. West China Medical Journal, 2017, 32(3): 392-394. doi: 10.7507/1002-0179.201512213 Copy

1.	杨建泉. 连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾衰的比较研究. 中国卫生产业, 2012, 10(25): 20-21.
2.	宋纲, 刘丽娟. 连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾衰的对照研究. 四川医学, 2013, 34(4): 555-556.
3.	王吉萍, 傅康才. 连续性肾脏替代治疗在多脏器功能障碍患者中的临床疗效. 中国现代医生, 2012, 50(33): 47-48, 51.
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5.	张岩郅, 苏伟, 尚有全, 等. 带袖套的中心静脉留置导管相关性感染的危险因素及干预分析. 内蒙古中医药, 2010, 29(21): 148-149.
6.	陈献广, 吴华, 孙慧娟. 维持性血液透析患者持续质量改进对预后的影响. 北京医学, 2011, 33(2): 111-115.
7.	曾蜀春, 简讯, 胡诗德, 等. 连续性肾替代联合血液灌流治疗重症感染AKI的临床疗效观察. 西部医学, 2015, 27(2): 203-205.
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9.	李琴, 姚坤花, 蒋玉兰. 连续肾脏替代疗法治疗重症急性肾功能衰竭的护理探讨. 中外医疗, 2014, 33(5): 160-161.
10.	郭风玲, 陈磊, 周瑾, 等. 连续性肾脏替代治疗与间歇性血液透析治疗伴急性肾衰竭的多器官功能障碍综合征疗效的Meta分析. 哈尔滨医科大学学报, 2014, 48(1): 77-84.
11.	邹懿, 王明初, 程宗华, 等. 重症急性肾功能衰竭应用CRRT比照IHD的效果研究. 当代医学, 2014, 20(2): 3-4.
12.	陈小嫦, 陈妙娴, 郑禄城, 等. 连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾功能衰竭的对照研究. 吉林医学, 2013, 34(3): 445-446.
13.	邵凤民, 寇灵芝, 程巧玲, 等. 连续性肾脏替代与间歇性血液透析治疗重症急性肾衰的比较研究. 实用诊断与治疗杂志, 2006, 20(2): 79-81.
14.	陈光权. 连续性肾脏替代疗法与间歇性血液透析治疗重症急性肾功能衰竭的比较分析. 吉林医学, 2013, 34(21): 4263-4264.
15.	祝亮. 采用连续性肾脏替代与间歇性血液透析治疗重症急性肾衰竭的临床效果对比研究. 临床和实验医学杂志, 2014, 13(6): 476-478.
16.	寇敏, 李凤英, 康乃新, 等. 连续性肾脏替代与间歇性血液透析治疗急性肾功能衰竭的生存率分析. 国际移植与血液净化杂志, 2011, 9(4): 31-35.

1. 杨建泉. 连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾衰的比较研究. 中国卫生产业, 2012, 10(25): 20-21.
2. 宋纲, 刘丽娟. 连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾衰的对照研究. 四川医学, 2013, 34(4): 555-556.
3. 王吉萍, 傅康才. 连续性肾脏替代治疗在多脏器功能障碍患者中的临床疗效. 中国现代医生, 2012, 50(33): 47-48, 51.
4. 覃丹平, 钟小仕, 陈辉, 等. 血液透析滤过与血液透析对维持性血液透析患者疗效的比较. 内科, 2011, 6(2): 109-112.
5. 张岩郅, 苏伟, 尚有全, 等. 带袖套的中心静脉留置导管相关性感染的危险因素及干预分析. 内蒙古中医药, 2010, 29(21): 148-149.
6. 陈献广, 吴华, 孙慧娟. 维持性血液透析患者持续质量改进对预后的影响. 北京医学, 2011, 33(2): 111-115.
7. 曾蜀春, 简讯, 胡诗德, 等. 连续性肾替代联合血液灌流治疗重症感染AKI的临床疗效观察. 西部医学, 2015, 27(2): 203-205.
8. 秦测. 连续性肾脏替代疗法在重症急性肾功能衰竭治疗中的价值. 临床合理用药杂志, 2014, 7(6): 101-102.
9. 李琴, 姚坤花, 蒋玉兰. 连续肾脏替代疗法治疗重症急性肾功能衰竭的护理探讨. 中外医疗, 2014, 33(5): 160-161.
10. 郭风玲, 陈磊, 周瑾, 等. 连续性肾脏替代治疗与间歇性血液透析治疗伴急性肾衰竭的多器官功能障碍综合征疗效的Meta分析. 哈尔滨医科大学学报, 2014, 48(1): 77-84.
11. 邹懿, 王明初, 程宗华, 等. 重症急性肾功能衰竭应用CRRT比照IHD的效果研究. 当代医学, 2014, 20(2): 3-4.
12. 陈小嫦, 陈妙娴, 郑禄城, 等. 连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾功能衰竭的对照研究. 吉林医学, 2013, 34(3): 445-446.
13. 邵凤民, 寇灵芝, 程巧玲, 等. 连续性肾脏替代与间歇性血液透析治疗重症急性肾衰的比较研究. 实用诊断与治疗杂志, 2006, 20(2): 79-81.
14. 陈光权. 连续性肾脏替代疗法与间歇性血液透析治疗重症急性肾功能衰竭的比较分析. 吉林医学, 2013, 34(21): 4263-4264.
15. 祝亮. 采用连续性肾脏替代与间歇性血液透析治疗重症急性肾衰竭的临床效果对比研究. 临床和实验医学杂志, 2014, 13(6): 476-478.
16. 寇敏, 李凤英, 康乃新, 等. 连续性肾脏替代与间歇性血液透析治疗急性肾功能衰竭的生存率分析. 国际移植与血液净化杂志, 2011, 9(4): 31-35.

West China Medical Journal

Efficacy comparison between continuous renal replacement therapy and intermittent hemodialysis in the treatment of severe acute renal failure

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