Clinical Effects of Two Different Autolytic Debridement on Subcutaneous Wounds_West China Medical Journal

Authors：

 DaiYongjing ¹ ,  FengWei ² , LiHongju ¹ , LiMiaomiao ¹ , ZhangMingxue ³

1. Orthopedic Rehabilitation Ward;General Hospital of PLA, Beijing 100853, P. R. China;
2. Oncology Center;General Hospital of PLA, Beijing 100853, P. R. China;
3. Nursing Department;General Hospital of PLA, Beijing 100853, P. R. China;

Corresponding author：

FengWei, Email: fengwei301@hotmail.com

Keywords：

Autolytic debridement; Subcutaneous tissue; Wound

DOI：

10.7507/1002-0179.201600406

Video：

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Objective To evaluate the effects of two different autolytic debridment on subcutaneous wounds. Methods Thirty-eight patients with subcutaneous wounds treated from January to December 2015 were numbered according to the sequence of admission, and were randomly divided into trial group and control group, with 19 patients in each group. All the patients had yellow surface. Patients in the control group were treated with amorphous hydrogel, while those in the trial group were treated with both amorphous hydrogel and alginate dressing. Then, we compared the two groups in terms of the debridement time, frequency of changing dressing, granulation growth, wound contraction rate at the end of debridement period, and leakage rate. Results The debridement time in the trial group was (21.11±5.86) days, and it was significantly shorter than that in the control group[(26.69±9.68) days] (P<0.05); the frequency of changing dressing was (7.21±2.12) times, which was less than that in the control group[(9.37±3.32) times] (P<0.05); and granulation growth was better than that in the control group (2.58±0.61 vs. 1.95±0.71, P<0.05). The wound contraction rate at the end of debridement period in the trial group was (47.00±26.24)%, which was higher than that in the control group[(29.03±22.62)%] (P<0.05); and the leakage rate (0.0%) was lower than the control group (3.3%) (P<0.05). Conclusion Using amorphous hydrogel and alginate dressing for subcutaneous wounds is better than amorphous hydrogel alone for autolytic debridement, and can lower the leakage rate.

Citation： DaiYongjing, FengWei, LiHongju, LiMiaomiao, ZhangMingxue. Clinical Effects of Two Different Autolytic Debridement on Subcutaneous Wounds. West China Medical Journal, 2016, 31(9): 1488-1491. doi: 10.7507/1002-0179.201600406 Copy

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13.	Vogt PM, Andree C, Breuing K, et al. Dry, moist, and wet skin wound repair[J]. Ann Plast Surg, 1995, 34(5):493-500.
14.	朱守林. 湿性疗法在慢性伤口处理中的应用观察[J]. 实用临床医药杂志, 2010, 14(6):67-69.
15.	刘冰, 叶兰萍. 水凝胶敷料联合复方紫草油在Ⅱ度烧伤创面中的应用[J]. 中国美容医学, 2014, 23(16):1332.
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1. 蒋琪霞, 李晓华. 清创方法及其关键技术的研究进展[J]. 中华护理杂志, 2009, 44(11):1045-1047.
2. 邓晓琴, 彭李华, 何斌, 等. 创面床准备理论在慢性伤口中的应用研究[J]. 现代医药卫生, 2016, 32(9):1373-1375.
3. 阙华发. 创面床准备理论与糖尿病性足溃疡的中医干预策略[J]. 中国中西医结合外科杂志, 2013, 19(3):346-348.
4. 吕娟, 宁宁, 叶霞, 等. 临床实施医护一体化伤口治疗模式[J]. 华西医学, 2012, 27(5):741-743.
5. 左建荣, 廖灯彬, 朱红, 等. 骨科医护一体化伤口管理成效[J]. 华西医学, 2013, 28(9):1448-1450.
6. Winter GD. Formation of the scab and the rate of epithelization of superficial wounds in the skin of young domestic pig[J]. Nature, 1962, 193(8):293-294.
7. 陈冰, 罗娜, 孙伟龙, 等. 10%氯化钠在Ⅲ期压疮清创期的应用研究[J]. 华西医学, 2015, 30(10):1818-1820.
8. 蒋琪霞, 徐格林, 刘新峰. 神经内科患者压疮不同清创方法的效果[J]. 中华护理杂志, 2009, 44(3):197-200.
9. 梁明娟, 林瑞燕, 区咏仪. 自溶性清创结合外科清创处理乳腺癌术后胸壁皮瓣坏死的临床实践[J]. 岭南现代临床外科, 2011, 11(5):392.
10. Brett DW. A review of moisture-control dressings in wound care[J]. J Wound Ostomy Continence Nurs, 2006, 33(6, S):S3-S8.
11. Eriksson E, Vranckx J. Wet wound healing:from laboratory to patients to gene therapy[J]. Am J Surg, 2004, 188(1A, S):36S-41S.
12. Field FK, Kerstein MD. Overview of wound healing in moist environment[J]. Am J Surg, 1994, 167(1A):2S-6S.
13. Vogt PM, Andree C, Breuing K, et al. Dry, moist, and wet skin wound repair[J]. Ann Plast Surg, 1995, 34(5):493-500.
14. 朱守林. 湿性疗法在慢性伤口处理中的应用观察[J]. 实用临床医药杂志, 2010, 14(6):67-69.
15. 刘冰, 叶兰萍. 水凝胶敷料联合复方紫草油在Ⅱ度烧伤创面中的应用[J]. 中国美容医学, 2014, 23(16):1332.
16. 葛小静, 章宏伟, 史京萍, 等. 藻酸盐银联合水凝胶敷料对慢性创面愈合的作用[J]. 中国组织工程研究, 2012, 16(3):539-542.

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