Interpretation of <i>Chinese Expert Consensus on Transcatheter Tricuspid Valve Intervention Therapy</i>_West China Medical Journal

Authors：

LIN Dawei ,  PAN Wenzhi

Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, National Clinical Research Center for Interventional Medicine, Shanghai 200032, P. R. China;

Corresponding author：

PAN Wenzhi, Email: peden@sina.com

Keywords：

Tricuspid regurgitation; transcatheter tricuspid valve intervention; expert consensus; interpretation

DOI：

10.7507/1002-0179.202509184

Video：

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Tricuspid regurgitation (TR) is a common cardiac valve disease for which conventional medical therapy offers limited benefits and surgical intervention carries significant risks. With advancements in transcatheter tricuspid valve intervention (TTVI) techniques, it has emerged as an important treatment option for patients with severe TR who are at high surgical risk. Based on Chinese Expert Consensus on Transcatheter Tricuspid Valve Intervention Therapy, this article provides an in-depth discussion on key aspects including TR pathological classification and prognosis, indication criteria, treatment strategies, selection of TTVI devices, study endpoints, and multidisciplinary team building. The aim is to elucidate the content of the consensus, enhance readers’ systematic understanding of TTVI, and promote the safe and standardized adoption of this technology in China.

1.	中国医师协会心血管内科医师分会结构性心脏病学组, 苏州工业园区东方华夏心血管健康研究院, 潘文志, 等. 三尖瓣反流经导管治疗的中国专家共识. 中国介入心脏病学杂志, 2024, 32(10): 551-561.
2.	Praz F, Borger MA, Lanz J, et al. 2025 ESC/EACTS guidelines for the management of valvular heart disease. Eur Heart J, 2025, 29: ehaf194.
3.	Maisano F, Hahn R, Sorajja P, et al. Transcatheter treatment of the tricuspid valve: current status and perspectives. Eur Heart J, 2024, 45(11): 876-894.
4.	Hahn RT, Lawlor MK, Davidson CJ, et al. Tricuspid valve academic research consortium definitions for tricuspid regurgitation and trial endpoints. J Am Coll Cardiol, 2023, 82(17): 1711-1735.
5.	Topilsky Y, Maltais S, Medina Inojosa J, et al. Burden of tricuspid regurgitation in patients diagnosed in the community setting. JACC Cardiovasc Imaging, 2019, 12(3): 433-442.
6.	Adamo M, Chioncel O, Pagnesi M, et al. Epidemiology, pathophysiology, diagnosis and management of chronic right-sided heart failure and tricuspid regurgitation. A clinical consensus statement of the Heart Failure Association (HFA) and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC. Eur J Heart Fail, 2024, 26(1): 18-33.
7.	Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. Circulation, 2021, 143(5): e35-e71.
8.	Vahanian A, Beyersdorf F, Praz F, et al. 2021 ESC/EACTS Guidelines for the management of valvular heart disease. EuroIntervention, 2022, 17(14): e1126-e1196.
9.	Wang TKM, Griffin BP, Miyasaka R, et al. Isolated surgical tricuspid repair versus replacement: meta-analysis of 15 069 patients. Open Heart, 2020, 7(1): e001227.
10.	Sorajja P, Whisenant B, Hamid N, et al. Transcatheter repair for patients with tricuspid regurgitation. N Engl J Med, 2023, 388(20): 1833-1842.
11.	Lurz P, Besler C, Schmitz T, et al. Short-term outcomes of tricuspid edge-to-edge repair in clinical practice. J Am Coll Cardiol, 2023, 82(4): 281-291.
12.	Kodali SK, Hahn RT, Davidson CJ, et al. 1-year outcomes of transcatheter tricuspid valve repair. J Am Coll Cardiol, 2023, 81(18): 1766-1776.
13.	Taramasso M, Benfari G, van der Bijl P, et al. Transcatheter versus medical treatment of patients with symptomatic severe tricuspid regurgitation. J Am Coll Cardiol, 2019, 74(24): 2998-3008.
14.	Gerçek M, Rudolph V, Arnold M, et al. Transient acute right coronary artery deformation during transcatheter interventional tricuspid repair with the Cardioband tricuspid system. EuroIntervention, 2021, 17(1): 81-87.
15.	Zhang X, Jin Q, Li W, et al. Transcatheter annuloplasty with the K-clip system for tricuspid regurgitation: one-year results from the TriStar study. EuroIntervention, 2025, 21(5): e262-e271.
16.	Zhang X, Lin D, Li W, et al. 1-year outcomes of transcatheter tricuspid annuloplasty for patients with severe atrial functional tricuspid regurgitation. JACC Cardiovasc Interv, 2024, 17(23): 2843-2844.
17.	Lin DW, Zou LW, Miao JX, et al. Outcomes of K-clip implantation for functional tricuspid regurgitation accompanied with persistent atrial fibrillation. J Cardiovasc Dev Dis, 2025, 12(2): 55.
18.	Lin D, Jin Q, Miao J, et al. Transcatheter tricuspid annuloplasty in tricuspid regurgitation patients with right ventricular-pulmonary arterial uncoupling. JACC Asia, 2025, 5(3): 424-433.
19.	Lurz P, Hahn RT, Kodali S, et al. Tricuspid valve replacement outcomes by baseline tricuspid regurgitation severity: the TRISCEND II trial. Eur Heart J, 2025, 29: ehaf676.
20.	Sun Z, Li H, Zhang Z, et al. Twelve-month outcomes of the LuX-Valve for transcatheter treatment of severe tricuspid regurgitation. EuroIntervention, 2021, 17(10): 818-826.
21.	Zhang Y, Lu F, Li W, et al. A first-in-human study of transjugular transcatheter tricuspid valve replacement with the LuX-Valve Plus system. EuroIntervention, 2023, 18(13): e1088-e1089.
22.	Kar S, Makkar RR, Whisenant BK, et al. Two-year outcomes of transcatheter edge-to-edge repair for severe tricuspid regurgitation: the TRILUMINATE pivotal randomized controlled trial. Circulation, 2025, 151(23): 1630-1638.
23.	Addetia K, Miyoshi T, Amuthan V, et al. Normal values of three-dimensional right ventricular size and function measurements: results of the world alliance societies of echocardiography study. J Am Soc Echocardiogr, 2023, 36(8): 858-866.e1.

1. 中国医师协会心血管内科医师分会结构性心脏病学组, 苏州工业园区东方华夏心血管健康研究院, 潘文志, 等. 三尖瓣反流经导管治疗的中国专家共识. 中国介入心脏病学杂志, 2024, 32(10): 551-561.
2. Praz F, Borger MA, Lanz J, et al. 2025 ESC/EACTS guidelines for the management of valvular heart disease. Eur Heart J, 2025, 29: ehaf194.
3. Maisano F, Hahn R, Sorajja P, et al. Transcatheter treatment of the tricuspid valve: current status and perspectives. Eur Heart J, 2024, 45(11): 876-894.
4. Hahn RT, Lawlor MK, Davidson CJ, et al. Tricuspid valve academic research consortium definitions for tricuspid regurgitation and trial endpoints. J Am Coll Cardiol, 2023, 82(17): 1711-1735.
5. Topilsky Y, Maltais S, Medina Inojosa J, et al. Burden of tricuspid regurgitation in patients diagnosed in the community setting. JACC Cardiovasc Imaging, 2019, 12(3): 433-442.
6. Adamo M, Chioncel O, Pagnesi M, et al. Epidemiology, pathophysiology, diagnosis and management of chronic right-sided heart failure and tricuspid regurgitation. A clinical consensus statement of the Heart Failure Association (HFA) and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC. Eur J Heart Fail, 2024, 26(1): 18-33.
7. Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. Circulation, 2021, 143(5): e35-e71.
8. Vahanian A, Beyersdorf F, Praz F, et al. 2021 ESC/EACTS Guidelines for the management of valvular heart disease. EuroIntervention, 2022, 17(14): e1126-e1196.
9. Wang TKM, Griffin BP, Miyasaka R, et al. Isolated surgical tricuspid repair versus replacement: meta-analysis of 15 069 patients. Open Heart, 2020, 7(1): e001227.
10. Sorajja P, Whisenant B, Hamid N, et al. Transcatheter repair for patients with tricuspid regurgitation. N Engl J Med, 2023, 388(20): 1833-1842.
11. Lurz P, Besler C, Schmitz T, et al. Short-term outcomes of tricuspid edge-to-edge repair in clinical practice. J Am Coll Cardiol, 2023, 82(4): 281-291.
12. Kodali SK, Hahn RT, Davidson CJ, et al. 1-year outcomes of transcatheter tricuspid valve repair. J Am Coll Cardiol, 2023, 81(18): 1766-1776.
13. Taramasso M, Benfari G, van der Bijl P, et al. Transcatheter versus medical treatment of patients with symptomatic severe tricuspid regurgitation. J Am Coll Cardiol, 2019, 74(24): 2998-3008.
14. Gerçek M, Rudolph V, Arnold M, et al. Transient acute right coronary artery deformation during transcatheter interventional tricuspid repair with the Cardioband tricuspid system. EuroIntervention, 2021, 17(1): 81-87.
15. Zhang X, Jin Q, Li W, et al. Transcatheter annuloplasty with the K-clip system for tricuspid regurgitation: one-year results from the TriStar study. EuroIntervention, 2025, 21(5): e262-e271.
16. Zhang X, Lin D, Li W, et al. 1-year outcomes of transcatheter tricuspid annuloplasty for patients with severe atrial functional tricuspid regurgitation. JACC Cardiovasc Interv, 2024, 17(23): 2843-2844.
17. Lin DW, Zou LW, Miao JX, et al. Outcomes of K-clip implantation for functional tricuspid regurgitation accompanied with persistent atrial fibrillation. J Cardiovasc Dev Dis, 2025, 12(2): 55.
18. Lin D, Jin Q, Miao J, et al. Transcatheter tricuspid annuloplasty in tricuspid regurgitation patients with right ventricular-pulmonary arterial uncoupling. JACC Asia, 2025, 5(3): 424-433.
19. Lurz P, Hahn RT, Kodali S, et al. Tricuspid valve replacement outcomes by baseline tricuspid regurgitation severity: the TRISCEND II trial. Eur Heart J, 2025, 29: ehaf676.
20. Sun Z, Li H, Zhang Z, et al. Twelve-month outcomes of the LuX-Valve for transcatheter treatment of severe tricuspid regurgitation. EuroIntervention, 2021, 17(10): 818-826.
21. Zhang Y, Lu F, Li W, et al. A first-in-human study of transjugular transcatheter tricuspid valve replacement with the LuX-Valve Plus system. EuroIntervention, 2023, 18(13): e1088-e1089.
22. Kar S, Makkar RR, Whisenant BK, et al. Two-year outcomes of transcatheter edge-to-edge repair for severe tricuspid regurgitation: the TRILUMINATE pivotal randomized controlled trial. Circulation, 2025, 151(23): 1630-1638.
23. Addetia K, Miyoshi T, Amuthan V, et al. Normal values of three-dimensional right ventricular size and function measurements: results of the world alliance societies of echocardiography study. J Am Soc Echocardiogr, 2023, 36(8): 858-866.e1.

West China Medical Journal

Latest ArticlesInterpretation of Chinese Expert Consensus on Transcatheter Tricuspid Valve Intervention Therapy

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