【摘要】 目的 观察光子嫩肤合并左旋维生素C导入治疗面部黄褐斑的临床疗效。 方法 2008年3月-2009年5月,105例黄褐斑患者随机分为两组,治疗组53例,用光子嫩肤治疗2个疗程后用左旋维生素C导入,1次/周,持续2个月;对照组52例,单纯使用光子嫩肤治疗后进行防晒、护肤治疗2个月。 结果 治疗组有40例黄褐斑消失,13例色斑明显减淡;对照组有12例黄褐斑消失,26例色斑明显减淡,11例色斑减淡,3例无效。两组疗效比较,差异有统计学意义(P lt;0.05)。 结论 光子嫩肤合并左旋维生素C导入治疗面部黄褐斑安全、方便、疗效好,患者易于接受。
【Abstract】 Objective To observe the clinical efficacy of the treatment of facial melasma by intense pulsed light (IPL) photorejuvenation combined with vitamin C. Methods From March 2008 to May 2009, 105 patients with facial melasma were randomly divided into two groups. In the treatment group, there were 53 patients who were treated with vitamin C after IPL photorejuvenation once a week for two months. For the 52 patients in the control group, sunscreen and skin care treatment were carried out after IPL treatment for two months. Results In the treatment group, 40 patients’ melasma disappeared and 13 patients’ melasma dodged obviously. In the control group, 12 patients’ melasma disappeared and pigmentation existed more or less in 40 patients. Conclusion Treatment for facial melasma by IPL photorejuvenation combined with vitamin C is safe, convenient, and have good effect, which can be easily accepted by the patients.
Citation:
ZHANG Lanfang,LEI Ying,LIU Hongyan. Treatment of Facial Melasma with Intense Pulsed Light Photorejuvenation Combined with Vitamin C. West China Medical Journal, 2011, 26(4): 544-546. doi:
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中国中西医结合学会皮肤性病专业委员会色素病学组. 黄褐斑的临床诊断和疗效标准[J].中国中西医结合皮肤性病学杂志, 2004, 3(1): 70.
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高景恒, 白伶珉, 李孟倩. 强脉冲光在美容外科应用的文献复习[J]. 实用美容整形外科杂志, 2003, 14(1): 39-42.
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Wu X, Hammer JA. Making sense of melanosome dynamics in mouse melanocytes[J]. Pigment Cell Res, 2000, 13(4): 241-247.
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徐天华, 李远宏, 祝霞, 等. 左旋维生素C美白、祛皱功效和安全性的临床研究[J]. 中国美容医学, 2009, 18(12): 1799.
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- 1. 欧阳恒, 杨志波. 颜面皮肤病中西医结合诊治[M]. 北京: 人民卫生出版社, 2003: 129-130.
- 2. 沈大为. 四种霜剂治疗黄褐斑[J]. 中国皮肤性病学杂志, 1994, 8(1): 54.
- 3. 闫仲生, 王晓红. 黄褐斑患者血清过氧化脂质及超氧化物歧化酶测定[J]. 临床皮肤科杂志, 1994, 23(6): 351.
- 4. 黄海滨, 梁建, 彭晓茹. 光子嫩肤技术治疗面部黄褐斑的临床观察[J]. 中国实用美容整形外科杂志, 2006, 2(1): 10-11.
- 5. 中国中西医结合学会皮肤性病专业委员会色素病学组. 黄褐斑的临床诊断和疗效标准[J].中国中西医结合皮肤性病学杂志, 2004, 3(1): 70.
- 6. Anderson RR, Parrish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation[J]. Science, 1983(4596), 220: 524-527.
- 7. 高景恒, 白伶珉, 李孟倩. 强脉冲光在美容外科应用的文献复习[J]. 实用美容整形外科杂志, 2003, 14(1): 39-42.
- 8. Lambert J, Vancoillie G, Naeyaert JM. Molecular motors and their role in pigmentation[J]. Cell Mol Biol, 1999, 45(7): 905-918.
- 9. Wu X, Hammer JA. Making sense of melanosome dynamics in mouse melanocytes[J]. Pigment Cell Res, 2000, 13(4): 241-247.
- 10. 徐天华, 李远宏, 祝霞, 等. 左旋维生素C美白、祛皱功效和安全性的临床研究[J]. 中国美容医学, 2009, 18(12): 1799.