【摘要】 目的 分析5-羟色胺再摄取抑制剂抗抑郁药物门诊治疗用药状况。 方法 抽取2010年8月23-29日四川大学华西医院精神科门诊1周的处方,采用限定日剂量分析法,分析用药频度、用药费用及合理用药情况。 结果 1周门诊量3 625例,其中焦虑抑郁性障碍1 518例(41.88%);诊断抑郁症者最多,为926例(61.0%),其次为焦虑症273例(18.0%)、焦虑状态132例(8.7%)、强迫症93例(6.1%),其余患者分别诊断为惊恐障碍、轻度抑郁症、抑郁状态及抑郁症伴焦虑等。用药频度由高到低依次为舍曲林、帕罗西汀、氟西汀、氟伏沙明和西酞普兰。日治疗消费额度由高到低依次:舍曲林、帕罗西汀、西酞普兰、氟西汀和氟伏沙明。 结论 5-羟色胺再摄取抑制剂抗抑郁药物的门诊用药符合临床合理用药规律,遵循循证医学证据用药。
Citation:
杨晓蓉,黄雪花,王艳. 精神科门诊5-羟色胺再摄取抑制剂抗抑郁药物用药状况分析. West China Medical Journal, 2011, 26(7): 1088-1089. doi:
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- 2. Eaton WW, Kalaydjian A, Scharfstein DO, et al. Prevalence and incidence of depressive disorder:the Baltimore ECA follow-up, 1998-2004[J]. Acta Psychiatr Scand, 2007, 116(3): 182-188.
- 3. Sareen J, Cox BJ, Afifi TO, et al. Combat and peacekeeping operations in relation to prevalence of mental disorders and perceived need for mental health care: findings from a large representative sample of military personnel[J]. Arch Gen Psychiatry, 2007, 64(7): 843-852.
- 4. 陈新谦, 金有豫, 汤光. 新编药物学[M]. 16版. 北京: 人民卫生出版社, 2007: 171-183.
- 5. Xie F, Tan CH, Li SC. Are they being used safely? A retrospective cross-sectional tertiary health care survey of selective serotonin reuptake inhibitors prescribing practice in Singapore[J]. Hum Psychopharmacol, 2005, 20(7): 459-465.
- 6. Madianos MG, Sarhan AL, Koukia E. Major depression across West Bank: A cross-sectional general population study[J]. Int J Soc Psychiatry, 2011, Mar 25. [Epub ahead of print].
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