目的：了解糖尿病患者踝肱指数的影响因素。方法：采用多普勒血流探测仪测定68例糖尿病患者的踝肱指数(Anklebranchial index，ABI)，ABI比值小于0.9为低ABI组，大于1.3为高ABI组，在0.9到1.3之间(含1.3)为正常组。结果：本组病例中ABI lt; 0.9者11例，占16.18%，ABI gt; 1.3者8例，占11.76%。低ABI组与正常组比较，前者年龄大、病程长，其脉压、HbA1C、TG、冠心病合并率、视网膜病变发生率明显增高。高ABI组与正常组比较，前者年龄大、病程长，其脉压、HbA1C、TG明显增高，HDLC明显降低。多因素logistic逐步回归分析显示年龄、病程是导致ABI异常的危险因素。结论：多个因素影响糖尿病踝肱指数变化。
Citation：
BAI Bing,SHE Yi,LI Zhipeng,et al.. Sdudy on the Effoding Factors of ABI in Diabetic Patients. West China Medical Journal, 2009, 24(2): 336-338. doi:
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- 1. 许樟荣.糖尿病足与周围动脉闭塞性病变[J].国外医学.内分泌学分册，2004，24(5)：312-314..
- 2. Belch JJ，Topol EJ，Agnelli G，et al.Critical issues in peripheral arterial disease detection and management：a call to action[J].Arch Intern Med，2003，163(8)：884-92..
- 3. Fowkes FG.The measurement of atherosclerotic peripheral after’iai disease and epidemiological surveys[J].Int J Epidemiol，1988，17(2)：248..
- 4. TemelkovaKurktschiev TS，Koehler C，Henkel E，et al.Postchailenge plasma glucose and glyeemic spikes are more strongly associated with atheroselerosis than fasting glucose or HbA1c level[J].Diabetes Care，2000，23(12)：1830..
- 5. The DECODE Study Group.European Diabetes Epidemiology Group.Glucose Tolerance and mortality：comparison of’WHO and American Diabetes Association diagnosis criteria[J].Lancet，1999，354(9179)：617..
- 6. Zander E，Heinke P，Reindel J，et al.Peripheral arterial disease in diabetes mellitus type 1 and type 2：are there different risk factors[J].Vasa，2002，31(4)：249-54..
- 7. 王一尘，段俊丽.脉压与心脑血管事件发生关系的研究[J].中国综合临床，2004，20(1)：21-3..
- 8. Doobay AV，Anand SS，et al.Sensitivity and specificity of the anklebrachial index to predict future cardiovascular outcomes：a systematic review[J].Thrombosis & Vascular Biology，2005，25(7)：1463-469..
- 9. Diehm C，Allenberg JR，Pittrow D，et al.Importance of the anklebrachial index(ABI)in the prevention of cardiovascular diseases.Ten questions and answers[J].Herz，2007，32(5)：404-09..
- 10. Heald CL，Fowkes FG，Murray GD，et al.Ankle Brachial Index Collaboration.Risk of mortality and cardiovascular disease associated with the anklebrachial index：Systematic review[J].Atherosclerosis，2006，189(1)：61-69.
- 11. Bonham PA.Get the LEAD out：noninvasive assessment for lower extremity arterial disease using ankle brachial index and toe brachial index measurements[J].Journal of Wound，Ostomy，& Continence Nursing，2006，33(1)：30-41.
