目的:探讨血管紧张素Ⅱ受体拮抗剂(ARB)对PAF患者P波离散度的影响。方法:观察48 例阵发性AF患者的最宽P 波和P 波离散度,并与ARB干预治疗3 个月后进行对比分析。结果:ARB治疗3个月后最宽P波、P 波离散度及P 波离散度≥40 ms的例数与治疗前比较差异有统计学意义 (P lt;0.05或 lt;0.01)。结论:ARB能减轻PAF患者心房结构重构及电重构,减少AF的发生。
Citation：
ZHAO Guozhong,CHEN Chen,FENG Xiaolan,et al.. Effects of Angiotensin Ⅱ Receptor Blocker on P Wave Deviation Degree in Patients with Paroxysmal Atrial Fibrillation. West China Medical Journal, 2009, 24(6): 1445-1446. doi:
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Copyright © the editorial department of West China Medical Journal of West China Medical Publisher. All rights reserved
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- 2. 郝亚荣,吴刚,黄从新,等. P波离散度对特发性阵发性心房颤动的预测价值[J]. 中国心脏起搏与心电生理杂志,2001,15 (3):199-121.
- 3. 郭继鸿.新概念心电图[M].第3版.北京大学医学出版社,2007:122-127.
- 4. 刘艳秋, 张振刚, 龚开政, 等. P 波变化、左房内径及左室舒张功能与冠心病阵发性心房颤动的关系[J]. 实用临床医药杂志, 2004, 8 (5) ∶108.
- 5. WRIGHT JW,HARDING JW. Brain agiotensin receptor subtypes AT and their functions[J]. Regul Rept,1995,59:269.
- 6. LOPEZ B, QUEREJETA R, VARO N, et al. Usefulness of serum carboxy terminal propep tide of procollagen type I in assessment of the cardio reparative ability of antihypertensive treatment in hypertensive patients[J]. Circulation, 2001, 104(2) ∶286.
- 7. NAKASHIMA H, KUMAGAI K, URATA H, et al. Angiotensin Ⅱ antagonist prevents electrical remodeling in atrial fibrillation[J]. Circulat ion, 2000, 101 (6) ∶2612.
- 8. KIM S,LWAO H. Molecular and cellular meehallisms of angiotensin Ⅱmediated cardiovascular and renal diseases[J]. Pharmacol Rev, 2000, 52:11-34.
