目的:比较罗格列酮钠片与二甲双胍片分别联合胰岛素治疗2型糖尿病的疗效和安全性。方法:40例单用胰岛素控制血糖不理想的2型糖尿病患者,随机分为A组,太罗组(罗格列酮钠片)(21例);B组,二甲双胍组(19例),进行为期16周的对照观察。结果:两组治疗后空腹及餐后2小时血糖及糖化血红蛋白(HbA1c)均呈有意义的下降(P lt;0.05),从下降幅度的百分率统计,太罗组下降幅度明显高于二甲双胍组。结论:太罗联合胰岛素治疗对于血糖的控制明显优于二甲双胍联合胰岛素治疗。
Citation：
XIONG Ping,DONG Gangqiang. Clinical Analysis of the Co-Administrated Rosiglitazone and Insulin in the Treatment of 40 Patients Type 2 Diabetes Mellitus. West China Medical Journal, 2009, 24(7): 1728-1730. doi:
Copy
Copyright © the editorial department of West China Medical Journal of West China Medical Publisher. All rights reserved
| 1. |
LEBOVITZ H E, DOLE J E, PATWARDHNAN R, et al. Rosiglitazone monotheray is effective in patients with type 2 diabetes[J]. J Cin Endocrinol Metab,2001,86:280-288.
|
| 2. |
STEWARD M, JONES N P, KRIEDER M, et al. Combiation effects if rosiglitazone and atorvas tatin on the dyslipidemia association with type 2 diabetes[J]. Diabetologia,2001,44(suppl 1):854.
|
| 3. |
MAYERSON A B, HUNDAL R S, DU FOR S, et al. The effects of rosiglitazone on insulin sensitiwity,lipolysis,and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes[J]. Diabetes,2002,51:797-802.
|
| 4. |
NOLAN J J, JONES N P, PATWARDHAN R, et al. Rosiglitazone taken once daily provides effective glycemic control in patients with Type 2 diabetes mellitus[J]. Diabetic Medicine,2000,17:287-294.
|
- 1. LEBOVITZ H E, DOLE J E, PATWARDHNAN R, et al. Rosiglitazone monotheray is effective in patients with type 2 diabetes[J]. J Cin Endocrinol Metab,2001,86:280-288.
- 2. STEWARD M, JONES N P, KRIEDER M, et al. Combiation effects if rosiglitazone and atorvas tatin on the dyslipidemia association with type 2 diabetes[J]. Diabetologia,2001,44(suppl 1):854.
- 3. MAYERSON A B, HUNDAL R S, DU FOR S, et al. The effects of rosiglitazone on insulin sensitiwity,lipolysis,and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes[J]. Diabetes,2002,51:797-802.
- 4. NOLAN J J, JONES N P, PATWARDHAN R, et al. Rosiglitazone taken once daily provides effective glycemic control in patients with Type 2 diabetes mellitus[J]. Diabetic Medicine,2000,17:287-294.
